After the Spanish Civil War, Ala Littoria invested in Iberia, the Spanish airline that was established following the demise of LAPE. Ala Littoria acquired 12,5 % of the airline and purchased three Junkers Ju 52 air frames without engines from Lufthansa, giving them to Iberia in lieu of capital.
Ala Littoria flew to destinations across Europe and Italian colonies in Africa. During the Second World War, Ala Littoria acted as a transport service for the Italian military. However the airline did not survive the war and was disbanded.