Alcohol sulfotransferase

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Alcohol sulfotransferase
Identifiers
EC number 2.8.2.2
CAS number 9032-76-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

Alcohol sulfotransferase is an enzyme that catalyzes the sulfate conjugation of primary and secondary alcohols including many hormones, neurotransmitters, drugs, and xenobiotic compounds.[1][2]

The chemical reaction is:

Alcohol sulfotransferase.svg
an alcohol + 3'-phosphoadenylyl-sulfate \rightleftharpoons adenosine 3',5'-bisphosphate + an organosulfate + H+

Family members[edit]

Human genes that encode alcohol sulfotransferases include:

See also[edit]

References[edit]

  1. ^ Lyon ES, Jakoby WB (July 1980). "The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases". Arch. Biochem. Biophys. 202 (2): 474–81. doi:10.1016/0003-9861(80)90452-X. PMID 6935986. 
  2. ^ Lyon ES, Marcus CJ, Wang JL, Jakoby WB (1981). "Hydroxysteroid sulfotransferase". Meth. Enzymol. 77: 206–13. doi:10.1016/S0076-6879(81)77027-7. PMID 6173569. 

External links[edit]