Aldolase C

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Aldolase C, fructose-bisphosphate
Protein ALDOC PDB 1xfb.png
PDB rendering based on 1xfb.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ALDOC ; ALDC
External IDs OMIM103870 MGI101863 HomoloGene21073 GeneCards: ALDOC Gene
EC number 4.1.2.13
RNA expression pattern
PBB GE ALDOC 202022 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 230 11676
Ensembl ENSG00000109107 ENSMUSG00000017390
UniProt P09972 P05063
RefSeq (mRNA) NM_005165 NM_009657
RefSeq (protein) NP_005156 NP_033787
Location (UCSC) Chr 17:
26.9 – 26.9 Mb
Chr 11:
78.32 – 78.33 Mb
PubMed search [1] [2]

Aldolase C, fructose-bisphosphate, also known as ALDOC, is an enzyme that, in humans, is encoded by the ALDOC gene.[1][2]

Function[edit]

This gene encodes a member of the class I fructose-bisphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively.[1]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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GlycolysisGluconeogenesis_WP534 go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to Entrez go to article go to article go to article go to article go to article go to WikiPathways go to article go to Entrez go to article
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GlycolysisGluconeogenesis_WP534 go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to Entrez go to article go to article go to article go to article go to article go to WikiPathways go to article go to Entrez go to article
|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit|]]
Glycolysis and Gluconeogenesis edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534". 

References[edit]

  1. ^ a b "Entrez Gene: ALDOC aldolase C, fructose-bisphosphate". 
  2. ^ Rocchi M, Vitale E, Covone A, Romeo G, Santamaria R, Buono P, Paolella G, Salvatore F (June 1989). "Assignment of human aldolase C gene to chromosome 17, region cen----q21.1". Hum. Genet. 82 (3): 279–82. doi:10.1007/BF00291170. PMID 2731939. 

Further reading[edit]