January 30, 1960
St. Petersburg, Russia
|Occupation||Chairman, GenforMax LLC|
Alex Titomirov (born January 30, 1960) is an Russian-American businessman, and the co-founder and Chairman of GenforMax LLC Alex previously served as CEO and Chairman of InforMax Inc and is also a founder of several other companies.
A successful biotech CEO, Alex Titomirov founded one of the first bioinformatics companies - InforMax [NASDAQ, INMX] and brought it public ($1 billion market cap) with “the best biotech IPO” [Washington Post, 2000] in the State of Maryland.
Titomirov was a founder of several pioneering technologies in the field of cancer treatment at the Russian Academy of Sciences. He discovered a bacterial DHFR genetic effect that prolonged the lifespan in irradiated mice, and he was one of the original authors of stable gene transformation of skin cells in vivo using the pioneering technology of “shot gun” with tungsten micro projectiles.
Titomirov was invited to come to work in the United States by James Watson – a Nobel Prize winner and a pioneer in discovering the structure of DNA. He worked at the National Institutes of Health as well as in a small pharmaceutical company before starting his own company InforMax, Inc. in 1990. Titomirov has pioneered an expert system based on modeling of the drug discovery process. InforMax products are currently sold to over 65,000 pharma and biotech companies worldwide. InforMax was acquired by Invitrogen, a major bioscience company with $1.2 billion in annual revenues, headquartered in Carlsbad, California. In addition, Titomirov was one of the principal developers of the software infrastructure for the Human Genome Project, founded by James Watson.
Titomirov was a major contributor to the Genomics Approach of drug discovery – which is demonstrated to be one of the main accelerators of drug discovery process.
Titomirov earned his Ph.D. in 1986 at the Institute of Cytology at the Russian Academy of Sciences in St. Petersburg, Russia.
Dr. Titomirov pioneered the field of transforming animal cells with foreign DNA which had led to development of human DNA vaccines and was a major contribution to human genetics with more than 50 books written based on Dr. Titomirov's original article 
Dr. Titomirov is currently building GenforMax corporation dedicated to bringing DNA and RNA interpretation tools to the market of popular as well as professional DNA analysis. The company plans to provide the necessary DNA/RNA analysis tools to professionals (biotech and pharma companies) as well as to hospitals and private individuals.
Avicenna Pharmaceuticals Corp
Co-Founder of the Avicenna Pharmaceuticals - The innovative cancer treatment company. The novel discovery of the “Cancer Stem Cells” is enabling finding the drugs a lot more specific for each particular tumor. Employs the most prominent scientists of the world.
Dr. Alex Titomirov is a Founder, Chairman. The Supplement company specializing in polyphenols extractions of different berries which are very helpful in preventing cancer and other metabolic disorders. Dr. Titomirov financed 100% of company development.
Real Time Health Corporation
Dr. Alex Titomirov - Founder, Chairman and CEO: The preventive medicine company specializing in developing devices for measuring the concentration of different metabolites in the human body including PSA, insulin etc.
Dr. Alex Titomirov - Co-Founder and Chairman. A Stem Cell company with the mission of developing the non-embryonic stem cells for organ transplantation.
The Royall Titomirov Group Corporation
Dr. Alex Titomirov - Founder, Chairman. Merchant bank specializing in M&A and LBOs.
CEO/Chairman of the Board, InforMax, Inc. Company went public with the peak value of 1 billion USD (NASDAQ: INMX); InforMax was sold to Invitrogen in November, 2002. InforMax has successfully developed the biological software packages - Vector NTI and GenoMax which went through extensive evaluation and testing at different sites worldwide. InforMax had customers in 50 countries worldwide with the group of users over 65,000 researchers in thousands of companies and universities. InforMax Inc. was also assisting The National Center for Biotechnology Information (NCBI, NIH) with various programs including but not limited to the Human Genome Project, GenBank, Entrez, PubMed, and MedLine.
Bibliography (Selected Publications)
- Glebov, O.K., Titomirov, A.V., Pinaev, G.P., and Tomilin, N.V. Transformation of Chinese hamster cell by the plasmid pBR325::HS3::TK and the influence of TPA on stability of transformants (1982) Proc. Natl. Acad. Sci. of the USSR (Dokl. AN USSR, transl.) 267: 1496-1498
- Titomirov, A.V., Pereversev, A.E., Stepanian, L.I., Podgornaya, O.I., and Aprelikova, O.N. Transfection of bone marrow colony forming cells of mouse by the plasmid containing bacterial dihydrofolate reductase (DHFR) gene (1985) Cytology (Tsitologiya, Rus.) 27: 1183-1188.
- Titomirov, A.V., Aprelikova, O.N., Vaisman, B.L., and Tomilin, N.V. Transgenic mice containing procaryotic DHFR gene (1985) Cytology (Tsitologiya, Rus.) 27: 1374-1379.
- Pereversev, A.E., Titomirov, A.V., Stepanian, L.I., Podgornaya, O.I., and Aprelikova, O.N. Selection in vivo of colony forming cells transformed by bacterial DHFR gene (1986) Proc. Natl. Acad. Sci. USSR (Dokl. AN USSR, transl.) 288: 233-236.
- Tomilin, N.V., Titomirov, A.V., and Stepanian, L.I. Transformation of teratocarcinoma cells CBA 9H6 by bacterial DHFR gene (1987) Cytology (Tsitologiya, Rus.) 29:1385-1391.
- Titomirov, A.V., and Zelenin, A.V. New methods of transfection of mammalian cells: A Minireview (1988) Molecular Biology (Moscow, transl.) 22: 1445-1450.
- Zelenin, A.V., Titomirov, A.V., and Kolesnikov, V.A. Genetic transformation of mouse cultured cells with the help of high velocity mechanical DNA injection (1989) FEBS Letters 244: 65-67.
- Titomirov, A.V., Sukharev, S.N., and Kistanova, E. In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA (1990) Biochemica et Biophysica Acta, 1088: 131-134.
- Zelenin, A.V., Alimov, A.A., Titomirov, A.V. et al. High- velocity mechanical DNA transfer of chloramphenicol acetyl transferase gene into rodent liver, kidney and mammalian gland cells in organ explants and in vivo (1991) FEBS Lett. 280:94-96.
- Sukharev, S.S., Titomirov, A.V., and Klenchin, V.A. Electrically-Induced DNA Transfer into cells. (1994 Birkhauser, Boston) Jon A. Wolff Editor. pp 210–232.
- Titomirov, A.V. "List of books, based on Dr. Titomirov's DNA transformation article". Amazon.com.
- Titomirov, A.V., Sukharev, S.N., and Kistanova, E (1991). "In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA". Biochim. Biophys. Acta (Biochemica et Biophysica Acta, 1088: 131-134) 1088 (1): 131–4. doi:10.1016/0167-4781(91)90162-F. PMID 1703441.
- "InforMax Announces Strategic Bioinformatics Collaboration With the Whitehead Institute for Biomedical Research"
- "National Institutes of Health shows its strength"
- "InforMax Announces Release of Vector NTI Suite Version 6.0"
- "INFORMAX INC FORM S-1"
- "The newsletter of the oxford science park"
- "Analysis of bioinformatics industry"
- "Comment un génie russe a conquis la Biotech Valley" Pierre Briançon - January 20, 2000 - L'Expansion
- "Collaboration between French research organisation CNRS and InforMax on bioinformatics"
- "Genome Holds Key to Preventive Medicine" CHERYL A. THOMPSON
- "France Champion du monde ? C'est possible ! " Alex Titomirov
- "BIOINFORMATICS" BUSINESS February 19, 2001
- "The Athena Group, Testimonials"
- "InforMax Vector NTI(R) Suite for molecular biology and genomics"
- "Viaken Systems and InforMax ForgeAlliance"
- "Data on protein interactions in humans to be available through new product from InforMax and AxCell Biosciences"
- "The Bioinformatics Gold"
- "Protein Science Bios"
- "InforMax Announces Genomax(TM) License Agreement With Cellular Genomics, Inc."
- "Computer cures " By Todd Shryock | Smart Business Cleveland | March 2000
- "Labs and companies seek their niches as work continues after the draft" NATURE | VOL 409 | FEBRUARY 15, 2001
- "Biomax News"
- "InforMax Inc. Bioinformatics Genomics Proteomics" Science Electronic Marketplace
- "Stemron Corporation Appoints Arthur M. Mandell President and Chief Executive Officer"
- "InforMax, Inc. Invites You to Join Its 2001 Second Quarter Financial Results Conference Call"
- "InforMax Announces Release of High-Throughput Research Architecture for Integrated Genomics Analysis"
- "What is Bioinformatics?"
- "InforMax Reports Fourth Quarter 2000 Revenues Of $5.8 Million"
- "Map Of Ww Protein Domain Helps Target Health Problems"
- "InforMax and Media Cybernetics Announce Distribution Agreement"
- "InforMax and SBI Announce Distribution Agreement"
- "James Bernstein, Alex Titomirov, Mark Murcko, John Thomson"
- "Who makes the best bioinformaticians?" Nature 409, 963 (February 15, 2001)
- "INFORMAX AND SBI ANNOUNCE DISTRIBUTION AGREEMENT"
- "Protein Science and Proteomics companies"
- "The Entrepreneurial Event Revised"
- "Informax and Axcell to host European seminar series: 'High-throughput research: Integrating genomics, expression, and proteomics for accelerated discovery research'"
- "Clusters, networks, and innovation" By Stefano Breschi, Franco Malerba
- "InforMax and UBI Sign Distribution Alliance for Informatics Software in Emerging Canadian Market" | Business Wire | June 20, 2002
- "Beware the End Of InforMax's Lockup Period" | The Washington Post | November 13, 2000 | Jerry Knight
- "InforMax and UBI Sign Distribution Alliance for Informatics Software in Emerging Canadian Market" Business Wire Article date:June 20, 2002
- "Founders of Maryland Bioscience and Medical Instrument Companies" Marsha R. B. Schachtel and Scott R. Heacock Johns Hopkins Institute for Policy Studies August 2002
- "Dr. Alex Titomirov Personal Web Page and contact information"
- "Zoominfo Titomirov profile"
- "Facebook page of Alex"
- "Alex Titomirov Linkedin"