Wojciechowicz was the Detroit Lions' first pick in the 1938 NFL Draft and won the starting center job in his first game as a Lion. Even though the Lions were in decline as a team, Alex would play with full effort on both offense and defense. In 1944, he demonstrated his defensive talents when he intercepted seven passes, a Lions record for several years. Although Wojciechowicz received his fair share of personal recognition, he yearned to play on a championship team. That never happened in Detroit. But when he was traded to the Philadelphia Eagles in the middle of the 1946 season, the two-time All-Pro selection joined a team that seemed poised to deliver him his dream.
At age 30, Wojciechowicz went to the Eagles as their most well-known defensive player. His veteran leadership made him a major contributor to the Eagles’ championship runs in 1948 and 1949. From the time he was picked as Detroit's number-one draft choice in 1938 until he retired in 1950 after 13 seasons of professional football.