Alexander Neil Bethune (August 28, 1800 - February 3, 1879) was a Church of England clergyman and bishop and the son of the Reverend John Bethune. He and his wife had ten children. They included Robert Henry Bethune, a noted banker with the Dominion Bank. He was a brother to John, also a clergyman, who was acting principal of McGill University from 1835 to 1846. He had other notable brothers. James Gray was a businessman, Angus was prominent in the fur trade and Donald was an important political figure in Upper Canada.
Alexander Neil Bethune inherited a diocese that was quite fragmented from methods and policies attributed to Strachan. These circumstances made his episcopate appear less successful. He was a humble man and some saw this as a weakness causing his message to be lost his generation.