Alglucerase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Alglucerase
Systematic (IUPAC) name
Human beta-glucocerebrosidase
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a692001
Legal status ?
Pharmacokinetic data
Half-life 3.6–10.4 min
Identifiers
CAS number 37228-64-1 YesY
ATC code A16AB01
DrugBank DB00088
UNII 27T56C7KK0 YesY
KEGG D09675 YesY
ChEMBL CHEMBL1201633 N
Chemical data
Formula C2532H3854N672O711S16 
Mol. mass 55597.4 g/mol
 N (what is this?)  (verify)

Alglucerase is a modified form of human β-glucocerebrosidase where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is the trade name of a citrate buffered solution of alglucerase manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease although it has been largely replaced by imiglucerase which is produced by recombinant DNA technology.[citation needed]

External links[edit]