He first appeared in a supporting role in Dariush Mehrjui's The Cow (1969) alongside Ezatollah Entezami, another famous Iranian actor. Nassirian then shined in the title role of Mr. Naive (1970), also by Mehrjui. His other memorable films include: The Postman (1971), The Cycle (1974), The Mandrake (1975), Kamalolmolk (1983), Mirza Norouz's Shoes (1985), Stone Lion (1986), Captain Khorshid (1987), The Scent of Joseph's Shirt (1995), and Iron Island (2005). He recently played the lead role in The Saturday Hunter (2011).