Prochaska was initially a museum curator and then an archivist at the Public Record Office, now The National Archives. From 1984 to 1992 she was administrator and deputy director at the Institute of Historical Research, University of London. She was Director of Special Collections at the British Library during 1992–2001. She was then head librarian at Yale University, USA, from 2001 to 2010. She became Principal of Somerville College from 1 September 2010. Since then she has been affectionally known as 'Ali P' by the student body. 
Prochaska was involved with the design of the first National Curriculum for history in the United Kingdom during 1989–90. She was a governor of London Guildhall University, now part of London Metropolitan University. She chaired the National Council on Archives and was a member of the Royal Commission on Historical Manuscripts. Prochaska is a Fellow of the Royal Historical Society and served as Vice-President 1995 - 99. In the US she chaired the Center for Research Libraries and several committees of the Association of Research Libraries, and lectured on subjects relating to archives and special collections. Prochaska currently lectures and publishes on topics related to national heritage and national identity.
Alice Prochaska is married to the historian Frank Prochaska.
- "Dr Alice Prochaska". Debrett's. Retrieved July 15, 2011.
- "Alice Prochaska". The Guardian. 18 November 2003. Retrieved July 15, 2011.
- "Yale Librarian Alice Prochaska To Step Down". Yale Bulletin. Yale University, USA. 17 July 2009. Retrieved July 15, 2011.
- "Alice Prochaska next Principal of Somerville College". Press release. University of Oxford, UK. 18 June 2009. Retrieved July 15, 2011.
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Dame Fiona Caldicott
|Principal of Somerville College, Oxford