All About Chemistry is the title of Semisonic's third and final studio album, released on March 13, 2001 through MCA Records. With this release, the band failed, at least in America, to capitalize on the momentum it had generated with the song "Closing Time" from their previous album, Feeling Strangely Fine. This had a softer edge than Feeling Strangely Fine and was not as popular with the fans. Its poor sales led to the band going on an unofficial hiatus. However, it has a five star rating by Q Magazine. The title track was featured on the soundtrack for 40 Days and 40 Nights.
The special edition of the album features cover art with orange (or pink in the U.K) fluid in the vials instead of the blue fluid of the original. It includes two bonus tracks, "Girlfriend" and "Ordinary Life"; instead of being tacked onto the end, they appear between "Get a Grip" and "Surprise."
As of 2013, All About Chemistry remains the band's last studio album.