Aloe emodin
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| Systematic (IUPAC) name | |
|---|---|
| 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | Oral |
| Identifiers | |
| CAS number | 481-72-1 |
| ATC code | None |
| PubChem | CID 10207 |
| ChemSpider | 9792 |
| KEGG | C10294 |
| ChEMBL | CHEMBL40275 |
| Chemical data | |
| Formula | C15H10O5 |
| Mol. mass | 270.24 |
| SMILES | eMolecules & PubChem |
|
|
| Physical data | |
| Melt. point | 223–224 °C (433–435 °F) Sublimes in CO2 stream |
| |
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Aloe emodin is a carcinogenic[1][2] anthraquinone present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.[3]
[edit] References
- ^ Badgwell, DB; Walker, CM; Baker, WT; Strickland, FM (2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular carcinogenesis 39 (3): 127–38. doi:10.1002/mc.10170. PMID 14991742.
- ^ National Toxicology, Program (2010). "Photocarcinogenesis study of aloe vera CAS NO. 481-72-1(Aloe-emodin) in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program technical report series (553): 7–33, 35–97, 99–103 passim. PMID 21031007.
- ^ The Merck Index, 12th Edition. 313.