alpha-Cyano-4-hydroxycinnamic acid

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α-Cyano-4-hydroxycinnamic acid
Alpha-cyano-4-hydroxycinnamic acid.svg
CAS number 28166-41-8 YesY
PubChem 6931228
ChEBI CHEBI:64340 YesY
Jmol-3D images Image 1
Molecular formula C10H7NO3
Molar mass 189.17 g mol−1
Appearance Yellow powder
Melting point 245–250 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

α-Cyano-4-hydroxycinnamic acid, also written as alpha-cyano-4-hydroxycinnamic acid and abbreviated CHCA, is a cinnamic acid derivative and is a member of the phenylpropanoid family. It is used as a matrix for peptides and nucleotides in MALDI mass spectrometry analyses.[1]

See also[edit]


  1. ^ Beavis, R. C.; Chaudhary, T.; Chait, B. T. (1992). "-α-Cyano-4-hydroxycinnamic acid as a matrix for matrix-assisted laser desorption mass spectrometry". Org. Mass Spectrom. 27 (2): 156–8. doi:10.1002/oms.1210270217.