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Not to be confused with acetylmethadol.[1]
Systematic (IUPAC) name
[(3R*,6R*)-6-dimethylamino-4,4-di(phenyl)heptan-3-yl] acetate
Clinical data
Legal status
CAS number 1553-31-7
ATC code None
Chemical data
Formula C23H31NO2 
Mol. mass 353.5034 g/mol

Alphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic.[2] Its levorotary enantiomer, levacetylmethadol, is an FDA-approved treatment for opioid addiction.[2] Alphacetylmethadol is very similar in structure to methadone, a widely-prescribed treatment for opioid addiction. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act, with an ACSCN of 9603 and a 2013 annual manufacturing quota of 2 grammes.[3]

See also[edit]


  1. ^ Richard Lawrence Miller (30 December 2002). The Encyclopedia of Addictive Drugs. Greenwood Publishing Group. p. 222. ISBN 978-0-313-31807-8. Retrieved 15 May 2012. 
  2. ^ a b Newman JL, Vann RE, May EL, Beardsley PM (October 2002). "Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats". Psychopharmacology 164 (1): 108–14. doi:10.1007/s00213-002-1198-8. PMID 12373424. 
  3. ^ 21 U.S.C. § 812(b)(1)