She started as a young Malayalam Serial artist and got her break with the serial Samayam. After that, She entered the movie industry after she became 'Kalathilakam' in the school youth festival in 2001. Her notable role in Malayalam was Meerayude Dukhavum Muthuvinte Swapnavum, where she played Meera the disabled sister of the lead actor. She also got the opportunity to play the sister of Mohanlal in the movie Hariharan Pillai Happy Aanu. But she didn't get the credit she needed to stay in the big screen, so she continued acting in television serials where she is very successful.
Ambili is daughter of Bala Chandran Pillai and Maheswari Amma of Gigi Bhavan at Chavara, Kulangarabhagam near Kollam district. She got married to film-serial cameraman Loval hailing from Thiruvananthapuram on March 27, 2009 at Kollam Bank Auditorium. They have a son Amarnath in 2012. She is a trained dancer in Bharathanatyam, Kuchipudi, Mohiniyattam & Folk Dance.