Ambrein
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| Ambrein | |
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(1R,2R,8aS)-1-[(E)-6-[(1S)-2,2-dimethyl-6-methylidenecyclohexyl]-4-methylhex-3-enyl]-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol |
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Other names
Ambrein |
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| Identifiers | |
| CAS number | 473-03-0 |
| PubChem | 11826112 |
| ChemSpider | 10000763  |
| Jmol-3D images | Image 1 Image 2 |
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| Properties | |
| Molecular formula | C30H52O |
| Molar mass | 428.73 g mol−1 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Ambrein is a fragrant substance that is used in the perfume industry. It is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodisiac effects of ambergris.[1]
It is a triterpene alcohol.
It has been shown to act as an analgesic[2] and increase sexual behaviour in rats,[3] providing some support for its traditional aphrodisiac use.
[edit] References
- ^ Sandroni P. Aphrodisiacs past and present: a historical review. Clinical Autonomic Research. 2001 Oct;11(5):303-7. doi:10.1007/BF02332975 PMID 11758796
- ^ Taha SA. Studies on the mode of action of ambrein as a new antinociceptive compound. Japanese Journal of Pharmacology. 1992 Oct;60(2):67-71. PMID 1479744
- ^ Taha SA, Islam MW, Ageel AM. Effect of ambrein, a major constituent of ambergris, on masculine sexual behavior in rats. Archives Internationales de Pharmacodynamie et de Therapie. 1995 Mar-Apr;329(2):283-94. PMID 8540767
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