Ambrein

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Ambrein
Ambrein.svg
Identifiers
CAS number 473-03-0 YesY
PubChem 11826112
ChemSpider 10000763 YesY
ChEBI CHEBI:78306 YesY
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C30H52O
Molar mass 428.73 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Ambrein is a triterpene alcohol that is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodisiac effects of ambergris.[1] Although ambrein itself is odorless, it serves as the biological precursor for a number of aromatic derivatives such as ambroxan and is thought to possess fixative properties for other oderants.

It has been shown to act as an analgesic[2] and increase sexual behaviour in rats,[3] providing some support for its traditional aphrodisiac use.

References[edit]

  1. ^ Sandroni P. Aphrodisiacs past and present: a historical review. Clinical Autonomic Research. 2001 Oct;11(5):303-7. doi:10.1007/BF02332975 PMID 11758796
  2. ^ Taha SA. Studies on the mode of action of ambrein as a new antinociceptive compound. Japanese Journal of Pharmacology. 1992 Oct;60(2):67-71. PMID 1479744
  3. ^ Taha SA, Islam MW, Ageel AM. Effect of ambrein, a major constituent of ambergris, on masculine sexual behavior in rats. Archives Internationales de Pharmacodynamie et de Therapie. 1995 Mar-Apr;329(2):283-94. PMID 8540767