Ambrose O'Connell (July 9, 1881 - October 12, 1962) was a judge of the United States Court of Customs and Patent Appeals.
O'Connell received a Ph.B. from the University of Notre Dame in 1907, and an LL.B. form Columbia Law School in 1910. He was an attorney for the Guarantee Trust Corporation in New York City from 1928 to 1932, and then assistant treasurer and office manager for the Democratic National Committee from 1932 to 1933. He was a special assistant to Postmaster General James Farley from 1933 to 1934, then Farley's executive assistant from 1934 to 1939, becoming a second assistant postmaster general in 1939 and first assistant postmaster general in 1940. In 1943, he was executive vice-chairman of the Democratic National Committee.
Nominated by President Franklin D. Roosevelt to the U.S. Court of Customs and Patent Appeals, O'Connell received his commission on June 10, 1944. He retired from active service on April 5, 1962, continuing in senior status until his death, later that year.