Amdoxovir

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Amdoxovir
Amdoxovir.png
Systematic (IUPAC) name
[(2R,4R)-4-(2,6-Diaminopurin-9-yl)-1,3-dioxolan-2-yl]methanol
Clinical data
Legal status
?
Identifiers
CAS number 145514-04-1 YesY
ATC code None
PubChem CID 124088
ChemSpider 110576 YesY
UNII 54I81H0M9C YesY
KEGG D02890 YesY
ChEMBL CHEMBL458876 YesY
NIAID ChemDB 005431
Chemical data
Formula C9H12N6O3 
Mol. mass 252.23 g/mol
 YesY (what is this?)  (verify)

Amdoxovir is a nucleoside reverse transcriptase inhibitor (NRTI) undergoing research for the treatment of HIV. It was discovered by Raymond F. Schinazi (Emory University) and C.K. Chu (University of Georgia). It is being developed by RFS Pharma.[1] Currently, it is in Phase II clinical studies.

References[edit]

  1. ^ "Amdoxovir". AIDSmeds.com. January 13, 2009. Archived from the original on March 21, 2008. Retrieved March 21, 2008. 

External links[edit]

  • Murphy RL, Kivel NM, Zala C, Ochoa C, Tharnish P, Mathew J, Pascual ML, Schinazi RF (2010). "Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals". Antivir Ther 15 (2): 185–192. doi:10.3851/IMP1514. PMID 20386073.