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|Operating agency||Iowa State University|
Ames Laboratory is a United States Department of Energy national laboratory located in Ames, Iowa. The Laboratory conducts research into various areas of national concern, including the synthesis and study of new materials, energy resources, high-speed computer design, and environmental cleanup and restoration. It is located on the campus of Iowa State University. It is operated for the United States Department of Energy under contract DE-AC02-07CH11358.
In January 2013 the U.S. Department of Energy announced the establishment of the Critical Materials Institute (CMI) at Ames Laboratory, with a mission to develop solutions to the domestic shortages of rare earth metals and other materials critical for U.S. energy security.
Ames Laboratory was formally established in 1947 by the United States Atomic Energy Commission as a result of the Ames Project's successful development of the most efficient process, the Ames Process, to produce high-purity uranium metal in large quantities for the Manhattan Project. In 1942, Iowa State College's Frank Spedding, an expert in the chemistry of rare earths, agreed to set up and direct a chemical research and development program to accompany the Manhattan Project's existing physics program. Its purpose was to produce high purity uranium from uranium ores. Harley Wilhelm developed new methods for both reducing and casting uranium metal, making it possible to cast large ingots of the metal and reduce production costs by as much as twentyfold. About one third (2 tons) of the uranium used in the first self-sustaining nuclear reaction at the University of Chicago was provided by this project. The Ames Project produced more than 2 million pounds (1,000 tons) of uranium for the Manhattan Project until industry took over the process in 1945.
The Ames project received the Army-Navy ‘E’ Award for Excellence in Production on October 12, 1945, signifying two-and-a-half years of excellence in industrial production of metallic uranium as a vital war material. Iowa State University is unique among educational institutions to have received this award for outstanding service, an honor normally given to industry. Other key accomplishments related to the project:
• Developed a process to recover uranium from scrap materials and convert it into good ingots.
• Developed an ion exchange process to separate rare earth elements from each other in gram quantities — something not possible with other methods.
• Developed a large-scale production process for thorium using a bomb-reduction method.
During the 1950s the Lab’s growing reputation for its work with rare earth metals rapidly increased its workload. As the country explored the uses of nuclear power, lab scientists studied nuclear fuels and structural materials for nuclear reactors. Processes developed at Ames Laboratory resulted in the production of the purest rare-earth metals in the world while at the same time reducing the price of the metals as much as 1,000 percent. In most cases, Lab facilities served as models for large-scale production of rare earth metals. Lab scientists took advantage of Iowa State University's synchrotron to pursue medium-energy physics research. Analytical chemistry efforts expanded to keep up with the need to analyze new materials.
Other key accomplishments from the 1950s:
• Developed processes for separating hafnium, niobium, barium, strontium, caesium and rubidium.
• Discovered a new isotope, phosphorus-33.
• Separated high-purity rare earth oxides in kilogram quantities.
• Developed a method of separating plutonium and fission products from spent uranium fuel.
• Produced high-purity yttrium metal in large quantities, shipping more than 18,000 pounds before industry took over the process.
During the 1960s the Lab reached peak employment as its scientists continued exploring new materials. As part of that effort, the Lab built a 5-megawatt heavy water reactor for neutron diffraction studies and additional isotope separation research. The United States Atomic Energy Commission established the Rare-Earth Information Center at Ames Lab to provide the scientific and technical communities with information about rare-earth metals and their compounds.
Other key accomplishments from the 1960s:
• Developed a process to produce thorium metal with a purity of 99.985 percent.
• Developed a process for producing high-purity vanadium metal for nuclear applications.
• Discovered a new isotope, copper-69.
• Conducted the first successful operation of an isotope separator connected to a reactor in order to study short-lived radioactivity produced by fission of uranium-235.
• Ames Lab Physicists succeed in growing the first large crystal of solid helium
During the 1970s, as the United States Atomic Energy Commission evolved into the United States Department of Energy, efforts diversified as some research programs closed and new ones opened. Federal officials consolidated reactor facilities, leading to the closure of the research reactor. Ames Laboratory responded by putting new emphasis on applied mathematics, solar power, fossil fuels and pollution control. Innovative analytical techniques were developed to provide precise information from increasingly small samples. Foremost among them was inductively coupled plasma-atomic emission spectroscopy, which could rapidly and simultaneously detect up to 40 different trace metals from a small sample.
Other key accomplishments from the 1970s:
• Developed a highly sensitive technique for the direct analysis of mercury in air, water, fish and soils.
• Developed a method for isolating minute amounts of organic compounds found in water.
• Developed a process for removing copper, tin and chromium from automotive scrap, yielding reclaimed steel pure enough for direct re-use.
• Developed an image intensifier screen that significantly reduced exposure to medical X-rays.
• Developed a solar heating module that could both store and transmit solar power.
In the 1980s research at Ames Laboratory evolved to meet local and national energy needs. Fossil energy research focused on ways to burn coal cleaner. New technologies were developed to clean up nuclear waste sites. High-performance computing research augmented the applied mathematics and solid-state physics programs. Ames Laboratory became a national leader in the fields of superconductivity and nondestructive evaluation. In addition, DOE established the Materials Preparation Center to provide public access to the development of new materials.
Other key accomplishments from the 1980s:
• Developed a liquid-junction solar cell that was efficient, durable and non-toxic.
• Received Defense Department funding to develop nondestructive evaluation techniques for aircraft.
• Became DOE’s lead laboratory for managing the environmental assessment of energy-recovery processes.
• Developed a new method for alloying pure neodymium with iron, producing the feedstock for a widely used neodymium magnet.
• Assisted in development of Terfenol which changes form in a magnetic field, making it ideal for sonar and transducer applications.
Encouraged by United States Department of Energy, in the 1990s Ames Laboratory continued its efforts to transfer basic research findings to industry for the development of new materials, products and processes. The Scalable Computing Laboratory was established to find ways of making parallel computing accessible and cost-effective for the scientific community. Researchers discovered the first non-carbon example of buckyballs, – a new material important in the field of microelectronics. Scientists developed a DNA sequencer that was 24 times faster than other devices, and a technique that assessed the nature of DNA damage by chemical pollutants.
Other key accomplishment of the 1990s:
• Developed HINT benchmarking technique that objectively compared computers of all sizes, now supported at BYU's HINT site.
• Improved method of high pressure gas atomization for turning molten metal into fine- grained metal powders.
• Predicted the geometry for a ceramic structure with a photonic band gap. These structures may improved the efficiency of lasers, sensing devices and antennas.
• Discovered a new class of materials that could make magnetic refrigeration a viable cooling technology for the future.
• Developed a high-strength lead-free solder.
Recent Developments 
The following are examples of how Ames Laboratory continues to contribute:
• Novel, platinum-modified nickel-aluminide coatings that deliver unprecedented oxidation and phase stability as bond coat layers in thermal barrier coatings, which could improve the durability of gas turbine engines, allowing them to operate at higher temperatures and extending their lifetimes.
• Research confirming negative refraction can be observed in photonic crystals in the microwave region of the electromagnetic spectrum, which moves physicists one step closer to constructing materials that exhibit negative refraction at optical wavelengths and realizing the much-sought-after superlens.
• Discovery of intermetallic compounds that are ductile at room temperature. could be used to produce practical materials from coatings that are highly resistant to corrosion and strong at high temperatures to flexible superconducting wires and powerful magnets.
• Development of heterogeneous catalysts whose ability to be recycled could help reduce costs for production of biodiesel fuel and eliminate waste-storage costs.
• Research on the photophysics of luminescent organic thin films and organic light-emitting diodes resulted in a novel integrated oxygen sensor and a new sensor company.
• Lead-free solder that is stronger, easier to use, stands up better in high-heat conditions, and is environmentally safe.
• A biosensor technology that helps to determine an individual’s risk of getting cancer from chemical pollutants.
• A capillary electrophoresis unit that can analyze multiple chemical samples simultaneously. This unit has applications in the pharmaceutical, genetics, medical, and forensics fields. This technology has been the basis of a spin-off business.
• Material for magnetic refrigeration that improves refrigerator efficiency by an estimated 40 percent in large-scale refrigeration units and air conditioners.
• Developed a mechanochemical process that is a solvent-free way to produce organic compounds in solid state. Being used to study new, complex hydride materials that could provide a solution for high-capacity, safe hydrogen storage needed to make hydrogen-powered vehicles viable.
• The design and demonstration of photonic band gap crystals, a geometrical arrangement of dielectric materials that allows light to pass except when the frequency falls within a forbidden range. These materials would make it easier to develop numerous practical devices, including optical lasers, optical computers, and solar cells.
As seen above, Ames Laboratory has broadened the scope of its research into various areas of national concern, including energy resources, high-speed computer design, environmental cleanup and restoration, and the synthesis and study of new materials.
Ames Laboratory Directors 
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Notable Alumni & Faculty 
Frank Spedding (B.S. 1925, M.S. 1926) (deceased), directed the chemistry phase of the Manhattan Project in World War II, which led to the world's first controlled nuclear reaction. He was Iowa State's second member of the National Academy of Sciences and the first director of the Ames Laboratory. Dr. Spedding won the Langmuir Award in 1933, Only Oscar K. Rice and Linus Pauling preceded him in this achievement. The award is now called the Award in Pure Chemistry of the American Chemical Society. He is the first to bear the title Distinguished Professor of Sciences and Humanities at Iowa State (1957). Further awards include: William H. Nichols Award of the New York section of the American Chemical Society (1952); the James Douglas Gold Medal from the American Institute of Mining, Metallurgical, and Petroleum Engineers (1961) for achievements in nonferrous metallurgy; and the Francis J. Clamer Award from the Franklin Institute (1969) for achievements in metallurgy.
Harley Wilhelm (Ph.D. 1931) (deceased), developed the most efficient process to produce uranium metal for the Manhattan Project, a process still used today.
Velmer A. Fassel (Ph.D. 1947)(deceased), internationally known for developing an analytical process, inductively coupled plasma-atomic emission spectroscopy (ICP-AES), used for chemical analysis in almost every research laboratory in the world; former deputy director of the Ames Laboratory.
Karl A. Gschneidner, Jr. (B.S. 1952, Ph.D 1957) Elected Fellow of the National Academy of Engineering in 2007, Gschneidner is acknowledged as one of the world’s foremost authorities in the physical metallurgy and thermal and electrical behaviors of rare earth materials. Additionally Gschneidner is a Fellow of the Minerals, Metals, and Materials Society, Fellow of the American Society for Materials International, and Fellow of the American Physical Society.
James Renier (Ph.D. 1955), chairman and chief executive officer of Honeywell Inc. (1988–93).
Darleane C. Hoffman (Ph.D. 1951), a 1997 recipient of the National Medal of Science, is one of the researchers who confirmed the existence of element 106, seaborgium.
John Weaver (Ph.D. 1973), named Scientist of the Year for 1997 by R&D Magazine. Weaver is currently head of the Department of Materials Science and Engineering at the University of Illinois, Urbana-Champaign.
James Halligan (B.S. 1962, M.S. 1965, Ph.D. 1967), president of Oklahoma State University (1994–present).
James W. Mitchell (Ph.D. 1970), named Iowa State University's first George Washington Carver Professor in 1994. He is also the winner of two R&D 100 Awards and the prestigious Percy L. Julian Research Award given by the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers for innovative industrial research. Mitchell is vice president of the Materials Research Laboratory at Bell Laboratories, Lucent Technologies.
Kai-Ming Ho, Che-Ting Chan, and Costas Soukoulis, physics and Ames Laboratory, were the first to design and demonstrate the existence of photonic band gap crystals, a discovery that led to the development of the rapidly expanding field of photonic crystals. Photonic crystals are expected to have revolutionary applications in optical communication and other areas of light technology. Costas Soukoulis is a recipient of the Descartes Prize for Excellence in Scientific Collaborative Research, the European Union’s highest honor in the field of science.
Dan Shechtman, winner of the 2011 Nobel Prize in Chemistry.
Pat Thiel, chemistry and Ames Laboratory, received one of the first 100 National Science Foundation Women in Science and Engineering Awards (presented in 1991).
Edward Yeung, chemistry and Ames Lab, first person to quantitatively analyze the chemical contents of a single human red blood cell, using a device that he designed and built; the development could lead to improved detection of AIDS, cancer and genetic diseases such as Alzheimer's, muscular dystrophy and Down's syndrome. Yeung has won four R&D 100 Awards and an Editor's Choice award from R&D Magazine for this pioneering work. He is also the 2002 recipient of the American Chemical Society Award in Chromatography for his research in chemical separations.
- Ames Laboratory
- Materials Preparation Center
- Iowa State University
- Iowa State University's Institute for Physical Research & Technology
- Biographical Memoir of Frank Spedding, by John. D. Corbett