The head of the fjord at Coordinates: . While the shores of the northern part separate peninsulas of the mainland of Greenland, the southern, progressively wider half of the fjord separates the large Ammassalik Island in the west from an archipelago of islands in the east and southeast, including the largest Apusiaajik Island.is formed by the confluence of two narrow, tributary fjords: Qingertivaq Fjord and Tasiilaq Fjord (one of two fjords of that name). The fjord has a north-to-south orientation in its northern part, to then turn midway to the south-west-south at approximately
The fjord is joined by narrow waterways with other waterbodies in the region: the Ikaasartivaq Strait separating Ammassalik Island from the mainland connects the fjord to the wider Sermilik Fjord in the west, while the Torsuut Tunoq sound and the Ikaasaartik Strait connect the fjord to the open North Atlantic.
- Tasiusarsik kangigdlek (35), near the western mouth of the fjord
- Kangarsik (34) and Norsit (25), on Kulusuk Island
- Umivik (19) and Kumarmiut (28), on Apusiaajik Island
- Ingmikertok (37), on a small island near Kumarmiut
- Norajik (47), on the island at the end of the wider, outer part of the fjord
There are three settlements in the vicinity of the fjord. The village of Kuummiit is the only village on its shores, located on the eastern coast of the central part of the fjord, perched on the tip of a partially glaciated mainland peninsula. The main settlement of the Ammassalik archipelago, Tasiilaq, is located near the mouth of the tributary Tasiilaq Fjord (Danish: Kong Oscars Havn), just south of the mouth of Ammassalik Fjord. Further to the southeast of the mouth, the village of Kulusuk occupies the northern shore of Kulusuk Island.
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- Tasiilaq, Saga Map, Tage Schjøtt, 1992