Amnion

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Amnion
Gray14.png
Surface view of embryo of Hylobates concolor.
Gray30.png
Human fetus, enclosed in the amnion.
Latin Amniosinas
Gray's p.56
MeSH Amnion
Code TE E6.0.1.2.0.0.9
For the alien race in Stephen R. Donaldson's The Gap Cycle, see Amnion (Gap Cycle).

The amnion is a membrane that when first formed, closely covers the embryo. It fills with fluid, the amniotic fluid which causes the amnion to expand and become the amniotic sac which serves to provide a protective environment for the developing embryo. It is a feature of the amniotes which included reptiles, birds, and mammals. Amphibians and fish are excluded from this group. The amnion stems from the extraembryonic somatic mesoderm on the outer side and the extraembryonic ectoderm on the inner side.

In humans[edit]

In the human embryo, the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion.

When first formed, the amnion is in contact with the body of the embryo, but about the fourth or fifth week amniotic fluid (also called liquor amnii) begins to accumulate within it. This fluid increases in quantity and causes the amnion to expand and ultimately to adhere to the inner surface of the chorion, so that the extra-embryonic part of the coelom is obliterated. The amniotic fluid increases in quantity up to the sixth or seventh month of pregnancy, after which it diminishes somewhat; at the end of pregnancy it amounts to about 1 liter.

The amniotic fluid allows the free movements of the fetus during the later stages of pregnancy, and also protects it by diminishing the risk of injury from without. It contains less than two percent solids, consisting of urea and other extractives, inorganic salts, a small amount of protein, and frequently a trace of sugar. That some of the liquor amnii is swallowed by the fetus is proved by the fact that epidermal debris and hairs have been found among the contents of the fetal alimentary canal.

In reptiles, birds, and many mammals[edit]

In reptiles, birds, and many mammals the amnion is developed in the following manner:

At the point of constriction where the primitive digestive tube of the embryo joins the yolk sac a reflection or folding upward of the somatopleure takes place.

This, the amniotic fold, first makes its appearance at the cephalic extremity, and subsequently at the caudal end and sides of the embryo, and gradually rising more and more, its different parts meet and fuse over the dorsal aspect of the embryo, and enclose a cavity, the amniotic cavity. This kind of amnion is known as pleuroamnion (formed by folding), as opposed to schyzoamnion (formed by delamination).

After the fusion of the edges of the amniotic fold, the two layers of the fold become completely separated, the inner forming the amnion, the outer the false amnion or serosa.

The space between the amnion and the serosa constitutes the extra-embryonic celom, and for a time communicates with the embryonic celom.

Cats and dogs are born inside of the amnion that is cut opened by their mothers and eaten.

Extra-amniotic pregnancy[edit]

Extra-amniotic pregnancy is a rare condition that can result from a rupture of the amnion, leading to development of the fetus within the extraembryonic coelom.[1]

Additional images[edit]

See also[edit]

References[edit]

  1. ^ TheFetus.net > Amniotic band syndrome By Luís Flávio Gonçalves, MD, Philippe Jeanty, MD, PhD. 1999-09-26-18

External links[edit]

This article incorporates text from a public domain edition of Gray's Anatomy.