Ampelopsin

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For other uses, see Ampelopsin (compounds).
Ampelopsin
Ampelopsin.svg
Identifiers
CAS number 27200-12-0 YesY
PubChem 161557
ChemSpider 16735660 YesY
ChEBI CHEBI:28429 YesY
Jmol-3D images Image 1
Properties
Molecular formula C15H12O8
Molar mass 320.25 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Ampelopsin, also known as dihydromyricetin, is a flavanonol, a type of flavonoid. It can be found in Cedrus deodara[1] or in the Japanese raisin tree (Hovenia dulcis).[2][3] It is also found in Erythrophleum africanum.[4]

The compound is credited with hepatoprotective effects observed in rodents.[5] Use of Hovenia species in traditional Chinese herbal medicine as a hangover cure has led to research into the potential action of dihydromyricetin in counteracting the effects of alcohol in the brain.[2][6][7]

References[edit]

  1. ^ Dihydroflavonols from Cedrus deodara. P.K. Agrawal, S.K. Agarwal and R.P. Rastogi, Phytochemistry, Volume 19, Issue 5, 1980, Pages 893–896, doi:10.1016/0031-9422(80)85133-8
  2. ^ a b Shen, Y.; Lindemeyer, A. K.; Gonzalez, C.; Shao, X. M.; Spigelman, I.; Olsen, R. W.; Liang, J. (2012). "Dihydromyricetin As a Novel Anti-Alcohol Intoxication Medication". Journal of Neuroscience 32 (1): 390–401. doi:10.1523/JNEUROSCI.4639-11.2012. PMC 3292407. PMID 22219299.  edit
  3. ^ Yoo, Seung Mi; Mun, Sungyong; Kim, Jin-Hyun (2006). "Recovery and pre-purification of (+)-dihydromyricetin from Hovenia dulcis". Process Biochemistry 41 (3): 567. doi:10.1016/j.procbio.2005.10.008. 
  4. ^ Optisch aktives Dihydromyricetin aus Erythrophleum africanum. R. Hänsel and J. Klaffenbach, Archiv der Pharmazie, 1961, Volume 294, Issue 3, pages 158–172, doi:10.1002/ardp.19612940306 (article in German)
  5. ^ Hase, K; Ohsugi, M; Xiong, Q; Basnet, P; Kadota, S; Namba, T (1997). "Hepatoprotective effect of Hovenia dulcis THUNB. On experimental liver injuries induced by carbon tetrachloride or D-galactosamine/lipopolysaccharide". Biological & Pharmaceutical Bulletin 20 (4): 381–5. doi:10.1248/bpb.20.381. PMID 9145214. 
  6. ^ "Chinese herbal medicine may provide novel treatment for alcohol abuse". UCLA Press Release. 01/05/2012. 
  7. ^ "Chinese tree extract stops rats getting drunk". New Scientist. 10/01/2012.