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Blau was born in Jerusalem, and grew up in the Meah Shearim neighbourhood. Like his brother Rabbi Moshe Blau who was a leader in the Agudat Israel movement, he was also active in the Aguda during the British Mandate era and was the editor of its newspaper, Kol Israel (Voice of Israel). But when the Aguda began to lean towards a modus vivendi with the Zionist leaders, Blau claimed that the Aguda had sold out to the Zionist movement and in 1937 broke away and founded Neturei Karta.
After the establishment of the State of Israel, Neturei Karta continued its staunch opposition to a Jewish state, in agreement with the Satmar Rebbe, Rabbi Joel Teitelbaum, author of the anti-Zionist Vayoel Moshe which advocated non-recognition of the State of Israel on theological grounds. Prior to the Six-Day War, Blau even went so far as to propose moving to Jordanian controlled East Jerusalem to avoid the secular temptations of modern Israel.
He was imprisoned many times for demonstrating against public violations of Shabbat, the conscription of religious women, the opening of a mixed-sex swimming pool, and other government policies. Most of his sentences were served at the Russian Compound, but he also did a five-month stint at Ramla prison. On two occasions he went out in public wearing sackcloth as a sign of protest.
Controversy on his second marriage
Blau's first wife, Hinda (née Weber), died in 1963. Because of an injury he sustained from shrapnel during the siege of Jerusalem in 1948 he could not remarry a woman who had been born Jewish. In 1965 he married to Ruth Ben-David http://fr.wikipedia.org/wiki/Ruth_Blau a convert 26 years younger than him. Born Madeleine Lucette Ferraille (1920-2000) to a Catholic family in Calais, Nord of France, https://fr.wikipedia.org/wiki/Ruth_Blau she got married first time in France in 5 septembre 1939 with Baud Henri,she had a child "Claude" and she divorced to her first husband in 31 juillet 1944. After an esoteric period in France  she converted to Judaism in 1950 with his child and went to Israel. She became interested in Judaism and then in Orthodox Judaism; but eventually abandoned her Judaism views in favor of the anti-Zionist views of Satmar and adopts the way of life of Blau founder anti-Zionist group Neturei Karta. She was involved on the child's kidnapping Yossele Schumacher affair. Ruth met Amram Blau in Israel via a shiduj. The match was opposed by Blau's two adult sons and by the rabbinical court of the Edah HaChareidis, so the couple had to move to Bnei Brak, but a year later they returned to Meah Shearim.
Blau died in 1974. He was interred at Har HaMenuchot. Ruth Blau continued to act as an independent wing of Neturei Karta.
- Zimmer, Uriel. "The Guardians of the City". Neturei Karta International. Retrieved 2007-01-22.
- Odenheimer, Micha (Spring 2006). "We Do Not Believe We Will Not Follow". Guilt and Pleasure (2).
- "Fifty Years Ago in the Forward". The Forward. 2006-09-22. Retrieved 2009-11-19.
- 1974 interview with Yitzchak Kahan, published in Sha'ah Tovah, 10 July 2009.
- Deuteronomy 23:2; Shulhan Arukh Even Haezer 5
- page 25.BLAU (Ruth) Les Gardiens de la cité. Histoire d'une guerre sainte Paris Flammarion 1978
- Yossele Schumacher affairhttp://en.wikipedia.org/wiki/Yossele_Schumacher_affair
- Cashman, Greer Fay (3 March 2000). "No stranger to controversy". The Jerusalem Post. Archived from the original on 19 January 2001.
- "The Lost Leader". Time. 1965-09-10. Retrieved 2007-01-22.
- "Neturei Karta Leader Adamant to Marry the Convert Ruth Ben David". Davar (in Hebrew). 14 July 1965.
- "Amram Blau Married to Ruth Ben David". Davar (in Hebrew). 3 September 1965.