Anal dysplasia

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Anal dysplasia is a pre-cancerous condition which occurs when the lining of the anal canal undergoes abnormal changes. It can be classified as low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) [1] Most cases are not associated with symptoms, but people may notice lumps in and around the anus.[2]

Causes[edit]

Anal dysplasia is most commonly linked to human papillomavirus (HPV), a usually sexually-transmitted infection.[3] HPV is the most common sexually transmitted infection.[4]

See also[edit]

References[edit]

  1. ^ Darragh, Teresa (October 2012). "The Lower Anogenital Squamous Terminology. Standardization Project for HPV-Associated Lesions:". Arch Pathol Lab Med 136: 1266-1297. 
  2. ^ Salit, Irving. "Fact Sheets: Anal dyspasia". Canadian Aids Treatment Information Exchange. Retrieved 2009-02-22. 
  3. ^ Palefsky, Joel M.; Holly, Elizabeth A.; Ralston, Mary L.; Jay, Naomi (February 1988). "Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeficiency Virus (HIV)–Positive and HIV-Negative Homosexual Men" (PDF). Departments of Laboratory Medicine, Stomatology, and Epidemiology Biostatistics, University of California, San Francisco. The Journal of Infectious Diseases Oxford University Press. Retrieved 2 March 2014. 
  4. ^ "CDC Fact Sheet - Incidence, Prevalence, and Cost of Sexually Transmitted Infections in the United States". CDC. February 2013. Retrieved 2 March 2014.