Anal dysplasia

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Anal dysplasia is a pre-cancerous condition which occurs when the mucosa lining of the anal canal undergo abnormal changes. During this condition, lesion, or visible pattern of clustered abnormal cells, appear. These cells may then progress from low-grade lesions to high-grade lesions.[1]

Symptoms include anal warts in and around the anus.[2]


Anal dysplasia is most commonly linked to human papillomavirus (HPV), a usually sexually-transmitted disease.[3] HPV is the most common sexually transmitted disease. Roughly 80% of people who have had one or two lifetime sex partners and 100% of people who have had five lifetime sex partners have had HPV infection, which may persist for life.[4]

See also[edit]


  1. ^ Young, Lee; Hanks D; Ung R; Stansell J (2004-07-11). The evaluation of anal dysplasia with anal cytology (PAP) followed by high resolution anoscopy (HRA) and biopsy in HIV-infected men. Positive Health Program/San Francisco General Hospital/University of California. 
  2. ^ Salit, Irving. "Fact Sheets: Anal dyspasia". Canadian Aids Treatment Information Exchange. Retrieved 2009-02-22. 
  3. ^ Palefsky, Joel M.; Holly, Elizabeth A.; Ralston, Mary L.; Jay, Naomi (February 1988). "Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeficiency Virus (HIV)–Positive and HIV-Negative Homosexual Men" (PDF). Departments of Laboratory Medicine, Stomatology, and Epidemiology Biostatistics, University of California, San Francisco. The Journal of Infectious Diseases Oxford University Press. Retrieved 2 March 2014. 
  4. ^ "CDC Fact Sheet - Incidence, Prevalence, and Cost of Sexually Transmitted Infections in the United States". CDC. February 2013. Retrieved 2 March 2014.