Anasarca

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Anasarca
ICD-10 R60.1
ICD-9 782.3
Plasmodium falciparum nephrosis edema PHIL 3894 lores.jpg

Anasarca, also known as "extreme generalized edema" is a medical condition characterised by widespread swelling of the skin due to effusion of fluid into the extracellular space. [1]

It is usually caused by liver failure (cirrhosis of the liver) or renal failure/disease and severe malnutrition/protein deficiency. The increase in salt and water retention caused by low cardiac output can also result in anasarca as a long term maladaptive response.

It can also be created from the administration of exogenous intravenous fluid.

Certain plant-derived anticancer chemotherapeutic agents, such as docetaxel, cause anasarca through a poorly understood capillary leak syndrome.

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