Born in Antonossa, in the Province of Álava (Basque County), Spain, Andrés Quintana joined the Franciscan Order in 1794 when he was 17 years of age. Nine years later he had completed his formation and achieved the priesthood in the province of Cantabria (in northern Spain), as did a great many of the Spanish missionaries. In 1804 he sailed to the New World to join the missionary College of San Fernando de Mexico, a springboard for all missionaries doing work in New Spain. There he received further instruction and preparation for his assignment to Mission Santa Cruz. Sailing from San Blas in 1805, he arrived at Monterey, capital of Spanish Alta California, and became one of two missionary fathers stationed at Mission Santa Cruz. He was killed at the mission on the evening of October 12, 1812, by Indians under his care. The following notation appears on his burial record: "[Frey Andrés was from] the province of Cantabria [Spain]. OFM Bro. José Casa Viader, minister of Mission Santa Clara, sang the mass over his body, accompanied by OFM Bro. Narciso Durán, minister of Mission San José, who learned of his passing and came to this mission. The deceased was found early in the morning dead in his bed of natural causes. [Subsequent notation:] A more thorough investigation was ordered by the military governor. During this investigation it was learned that he had been suffocated by Christian Indians of this mission and [Mission] Santa Clara. [Fr. Andrés] was summoned to the orchard of this mission where a patient feigned illness, and there he was suffocated [and his dead body returned to his quarters]."  According to another source, Brother Andrés was murdered because of his plans to use a metal-tipped whip to punish Indian converts. He is considered one of two martyr priests who served in the coastal missions of California.
- Santa Cruz Mission Burial 01124, October 13, 1812
- Leffingwell, p. 132
- Leffingwell, pp. 19, 132
- Leffingwell, Randy (2005). California Missions and Presidios: The History & Beauty of the Spanish Missions. Voyageur Press, Inc., Stillwater, MN. ISBN 0-89658-492-5.
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