Andrei Gruzdev is a Russian ski-orienteering competitor and world champion.
He received a gold medal in sprint at the 2002 World Ski Orienteering Championships in Borovetz, and a gold medal in the middle distance in Levi in 2005. In 2007 he won a gold medal in the relay event (with Kirill Veselov and Eduard Khrennikov). He has received two individual silver medal and three bronze medals at the world championships.
At the World Cup in Ski Orienteering in 2000 Gruzdev finished overall second, behind winner Eduard Khrennikov.