Andrew Quick is the great-grandson of David Quick, who was found dead in a 1930s Nazi fighter plane by Roland Deschain and his ka-tet before entering the city of Lud. Andrew leads the Grays, a group of inhabitants in Lud. Quick orders the capture of one of Roland's crew, Jake Chambers; moments after capturing the boy, Quick's forces are suddenly attacked. During the ensuing struggle between the Grays and Roland's ka-tet, Quick loses an eye and is shot in the head. He survives, however, to meet a man referring to himself as Richard Fannin, and gladly enlists to help find and kill Deschain.
Fannin claims to have chosen Quick because he reminds him of a man who once served him and whom he still has a sentimental spot for. He then asks Quick to repeat the phrase "My Life for You". This refers to King's novel The Stand and the character Trashcan Man, who subtly resembles Quick and the two may well be twinners.
Quick reappears in a minor role in The Dark Tower IV: Wizard and Glass. When Roland and his ka-tet reach a deserted and alternate Kansas from that of their own world, they travel down highway I-70, eventually reaching a green castle. The green castle and the events occurring between are almost an exact replica of The Wizard of Oz, with Quick turning out to be the man behind the curtain. Quick appears as an injured and mindless zombie serving Flagg. At the creature's command, he attempts to kill Roland's ka-tet, but Roland shoots and kills him.