Hyperandrogenism
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Hyperandrogenism is a medical condition characterized by excessive production and/or secretion of androgens.
It is one of the primary symptoms of polycystic ovary syndrome. In such cases, it presents with symptoms such as acne or hyperseborrhea, is frequent in adolescent girls and is often associated with irregular menstrual cycles. In most instances, these symptoms are transient and only reflect the immaturity of the hypothalamic-pituitary-ovarian axis during the first years following menarche.[1] Approximately three-quarters of patients with PCOS (by the diagnostic criteria of NIH/NICHD 1990) have evidence of hyperandrogenemia, with free testosterone being the single most predictive marker with ~60% of patients demonstrating supranormal levels.[2]
[edit] References
- ^ Christine Cortet-Rudelli, Didier Dewailly (Sep 21 2006). "Diagnosis of Hyperandrogenism in Female Adolescents". Hyperandrogenism in Adolescent Girls. Armenian Health Network, Health.am. http://www.health.am/gyneco/more/diagnosis-of-hyperandrogenism-in-female/. Retrieved 2006-11-21.
- ^ Huang A, Brennan K, Azziz R (April 2010). "Prevalence of hyperandrogenemia in the polycystic ovary syndrome diagnosed by the National Institutes of Health 1990 criteria". Fertil. Steril. 93 (6): 1938–41. doi:10.1016/j.fertnstert.2008.12.138. PMC 2859983. PMID 19249030. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2859983.
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