Angiopoietin-related protein 2

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Angiopoietin-like 2
Identifiers
Symbols ANGPTL2 ; ARP2; HARP
External IDs OMIM605001 MGI1347002 HomoloGene22695 GeneCards: ANGPTL2 Gene
RNA expression pattern
PBB GE ANGPTL2 219514 at tn.png
PBB GE ANGPTL2 213001 at tn.png
PBB GE ANGPTL2 213004 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23452 26360
Ensembl ENSG00000136859 ENSMUSG00000004105
UniProt Q9UKU9 Q9R045
RefSeq (mRNA) NM_012098 NM_011923
RefSeq (protein) NP_036230 NP_036053
Location (UCSC) Chr 9:
129.85 – 129.89 Mb
Chr 2:
33.22 – 33.25 Mb
PubMed search [1] [2]

Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene.[1][2]

Function[edit]

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.[2]

References[edit]

  1. ^ Kim I, Moon SO, Koh KN, Kim H, Uhm CS, Kwak HJ, Kim NG, Koh GY (Oct 1999). "Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting". J Biol Chem 274 (37): 26523–8. doi:10.1074/jbc.274.37.26523. PMID 10473614. 
  2. ^ a b "Entrez Gene: ANGPTL2 angiopoietin-like 2". 

Further reading[edit]