Anileridine

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Anileridine
Anileridine2DCSD.svg
Systematic (IUPAC) name
Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
AHFS/Drugs.com monograph
Legal status
Routes Tablets, injection
Pharmacokinetic data
Protein binding > 95%
Metabolism Hepatic
Identifiers
CAS number 144-14-9 YesY
ATC code N01AH05
PubChem CID 8944
DrugBank DB00913
ChemSpider 8600 YesY
UNII 71Q1A3O279 YesY
KEGG D02941 YesY
ChEBI CHEBI:61203 YesY
ChEMBL CHEMBL1201347 N
Chemical data
Formula C22H28N2O2 
Mol. mass 352.47 g/mol
Physical data
Melt. point 83 °C (181 °F)
 N (what is this?)  (verify)

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s.[1] It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.[2]

Administration[edit]

As tablets or injection.[3]

Pharmacokinetics[edit]

Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[4] It is mostly metabolized by the liver.

References[edit]

  1. ^ US Patent 2897204
  2. ^ "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008. 
  3. ^ "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010. 
  4. ^ "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008.