Anisocytosis

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Anisocytosis
Classification and external resources
ICD-10 R71
ICD-9 790.09
DiseasesDB 725

Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is found in anemia and other blood conditions. False diagnostic flagging may be triggered by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps.

The red cell distribution width (RDW) is a measurement of anisocytosis[1] and is calculated as a coefficient of variation of the distribution of RBC volumes divided by the mean corpuscular volume (MCV)

Increased RDW is seen in iron deficiency anemia, Thalassemia Major (Cooley's anemia), Thalassemia Intermedia and myelodysplastic syndromes

[edit] References

  1. ^ Barbara J. Bain (2006). Blood cells: a practical guide. Wiley-Blackwell. pp. 66–. ISBN 9781405142656. http://books.google.com/books?id=1k2CB7qgt-8C&pg=PA66. Retrieved 10 November 2010. 


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