Born in Kolkata India and abandoned by her mother, she was adopted by Lawrence Pratt and Rosalind Forber when she was 2 years old. she was Raised in Natick, Massachusetts, Forber-Pratt was diagnosed with transverse myelitis at four and a half months of age. The disorder left her paralyzed from the waist down. She began racing at the national level in 1993 with an appearance at the Junior National Wheelchair Games. She competed at the games three more times, in 1996, 1998, and 2003, and won a total of four gold, six silver, and two bronze medals. She is currently the World and American Record holder in the 200m. As a student at Natick High School she also competed in downhill skiing before graduating in 2002.
Forber-Pratt is a three-time graduate from the University of Illinois and is an alumni member of the school's wheelchair track and field team. She has received a bachelor's and master's degree  in Speech Language Pathology from Illinois and earned her doctorate of philosophy in human resource education in May 2012.
Her first major international competition was the 2007 Parapan American Games in Rio de Janeiro, where she won two gold medals in the 100 and 200 meter races and a bronze in the 400 meters. At the 2008 Beijing Paralympics, she won a bronze medal in the 400 meter T53 event with a personal best time of 56.79 seconds and another bronze in the 4×100 meter relay T53–T54. She also competed in the 100 and 200 meters in Beijing, finishing sixth and fourth, respectively.
Forber-Pratt is a Board Member of Disabled Sports USA, an organization founded in 1967 that provides opportunities for over 60,000 youth, wounded warriors and adults with disabilities to develop independence, confidence and fitness through participation in disabled sports each year.
Forber-Pratt is also an advocate and was involved in a legal battle with her high school in 2002, fighting for equal access to education for students with disabilities. She is assistant research professor at the beach center of disability at university of Kansas.
- Breitrose, Charlie (July 3, 2008). "She is among the elite". Natick Bulletin and Tab. Retrieved 2008-10-16.
- "Anjali Forber-Pratt". United States Olympic Committee. 2008. Retrieved 2008-10-16.
- "IPC Athletics Records". International Paralympic Committee. Retrieved 2011-05-31.
- "Records fall on day two". United States Olympic Committee. 2010. Retrieved 2010-07-20.
- "Amazing Anjali Forber-Pratt Continues to Amaze ... That's Doctor Anjali". 2012-03-13. Retrieved 2012-03-15.
- Bourgeois, Beth (September 10, 2008). "Three Medals for U.S. Track & Field Team; Jamison and Galli Win Gold, Forber-Pratt Comes Away with Bronze". United States Olympic Committee. Archived from the original on 3 October 2008. Retrieved 2008-10-16.
- Disabled Sports USA website = Board Members