Anprolene
From Wikipedia, the free encyclopedia
Anprolene is a registered trade name for ethylene oxide that belongs to Andersen Sterilizers.
Harold W. Andersen invented Anprolene in 1967[1] and used plastic bags and small ampoules, hence, substantially less ethylene oxide (EtO) than traditional chamber type sterilizers. The "bag method" of using ethylene oxide was particularly useful to Andersen whose invention of the first double lumen nasogastric tube was being used by his colleagues at Bellevue Hospital in New York, NY, where he was chief resident. At that time a single lumen Levin tube was employed clean and packaged, but not sterile. Andersen recognized the need and the Andersen Tube was packaged and sterilized with ethylene oxide. The US EPA registered Anprolene in 1968. Another bag method, Sterijet, was invented and used to sterilize Andersen Tubes and other medical devices.
Plastic, latex and rubber, and the like are "pourous" to Ethylene oxide so that EO or EtO diffuses through a series of bags containing a specific quantity of gas. The bag containing the items for sterilization concentrates the gas for enough time which is why it is called the "bag method" or "unit-dose gas diffusion method" [2]. Each sterilization cycle uses less than 18g of 100% EtO, hence every corner of a traditional EtO chamber type sterilizer that relies on tanks containing pounds of EO need not be filled.
The unit-dose, gas diffusion bag method is widely used where small quantities of goods require sterilization.
