Anti-nRNP

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Anti-nRNP is a type of antibody.[1][2]

They are autoantibodies against some ribonucleoproteins.[3]

One form of Anti-nRNP is antibodies towards snRNP70 (then called anti-snRNP70). Anti-snRNP70 antibodies can be elevated in mixed connective tissue disease.[4]

References[edit]

  1. ^ Migliorini P, Baldini C, Rocchi V, Bombardieri S (February 2005). "Anti-Sm and anti-RNP antibodies". Autoimmunity 38 (1): 47–54. doi:10.1080/08916930400022715. PMID 15804705. 
  2. ^ Brennan FM, Andrew EM, Williams DG, Maini RN (February 1988). "Anti-nRNP anti-nuclear antibody-secreting cells are represented in the B-lymphocyte repertoire of normal and MRL/MP-lpr/lpr lupus mice". Immunology 63 (2): 213–7. PMC 1454531. PMID 3258271. 
  3. ^ Satoh M, Richards HB, Hamilton KJ, Reeves WH (May 1997). "Human anti-nuclear ribonucleoprotein antigen autoimmune sera contain a novel subset of autoantibodies that stabilizes the molecular interaction of U1RNP-C protein with the Sm core proteins". J. Immunol. 158 (10): 5017–25. PMID 9144522. 
  4. ^ Negoro N, Kanayama Y, Takeda T, Koda S, Inoue T (July 1986). "A solid-phase radioimmunoassay for the detection of nRNP immune complexes". J. Immunol. Methods 91 (1): 83–9. doi:10.1016/0022-1759(86)90105-5. PMID 3722833.