Antithrombotic

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An antithrombotic is a drug which reduces thrombus formation.^[1]^[2]

Different antithrombotics affect different processes:

Antiplatelet drugs limit the migration or aggregation of platelets.
Anticoagulants limit the ability of the blood to clot.
Thrombolytic drugs act to dissolve clots after they have formed.

[edit] See also

Direct Xa inhibitor

[edit] References

v t e Pharmacology: major drug groups

Gastrointestinal tract/metabolism (A)	stomach acid (Antacids, H₂ antagonists, Proton pump inhibitors) Antiemetics Laxatives Antidiarrhoeals/Antipropulsives Anti-obesity drugs Anti-diabetics Vitamins Dietary minerals

Blood and blood forming organs (B)	Antithrombotics (Antiplatelets, Anticoagulants, Thrombolytics/fibrinolytics) Antihemorrhagics (Platelets, Coagulants, Antifibrinolytics)

Cardiovascular system (C)	cardiac therapy/antianginals (Cardiac glycosides, Antiarrhythmics, Cardiac stimulants) Antihypertensives Diuretics Vasodilators Beta blockers Calcium channel blockers renin-angiotensin system (ACE inhibitors, Angiotensin II receptor antagonists, Renin inhibitors) Antihyperlipidemics (Statins, Fibrates, Bile acid sequestrants)

Skin (D)	Emollients Cicatrizants Antipruritics Antipsoriatics Medicated dressings

Genitourinary system (G)	Hormonal contraception Fertility agents SERMs Sex hormones

Endocrine system (H)	Hypothalamic-pituitary hormones Corticosteroids (Glucocorticoids, Mineralocorticoids) Sex hormones Thyroid hormones/Antithyroid agents

Infections and infestations (J, P, QI)	Antimicrobials: Antibacterials (Antimycobacterials) Antifungals Antivirals Antiparasitics (Antiprotozoals, Anthelmintics, Ectoparasiticides) IVIG Vaccines

Malignant disease (L01-L02)	Anticancer agents (Antimetabolites, Alkylating, Spindle poisons, Antineoplastic, Topoisomerase inhibitors)

Immune disease (L03-L04)	Immunomodulators (Immunostimulants, Immunosuppressants)

Muscles, bones, and joints (M)	Anabolic steroids Anti-inflammatories (NSAIDs) Antirheumatics Corticosteroids Muscle relaxants Bisphosphonates

Brain and nervous system (N)	Analgesics Anesthetics (General, Local) Anorectics Anti-ADHD Agents Antiaddictives Anticonvulsants Antidementia Agents Antidepressants Antimigraine Agents Antiparkinson's Agents Antipsychotics Anxiolytics Depressants Entactogens Entheogens Euphoriants Hallucinogens (Psychedelics, Dissociatives, Deliriants) Hypnotics/Sedatives Mood Stabilizers Neuroprotectives Nootropics Neurotoxins Orexigenics Serenics Stimulants Wakefulness-Promoting Agents

Respiratory system (R)	Decongestants Bronchodilators Cough medicines H₁ antagonists

Sensory organs (S)	Ophthalmologicals Otologicals

Other ATC (V)	Antidotes Contrast media Radiopharmaceuticals Dressings

Antithrombotics (thrombolytics)

Antiplatelet drugs

Glycoprotein IIb/IIIa inhibitors	Abciximab Eptifibatide Tirofiban

ADP receptor/P2Y₁₂ inhibitors	thienopyridines (Clopidogrel Prasugrel Ticlopidine) nucleotide/nucleoside analogs (Cangrelor Elinogrel Ticagrelor)

Prostaglandin analogue (PGI2)	Beraprost Prostacyclin Iloprost Treprostinil

COX inhibitors	Acetylsalicylic acid/Aspirin^# Aloxiprin Carbasalate calcium Indobufen Triflusal

Thromboxane inhibitors	thromboxane synthase inhibitors (Dipyridamole Picotamide) receptor antagonist (Terutroban^†)

Phosphodiesterase inhibitors	Cilostazol Dipyridamole Triflusal

Other	Cloricromen Ditazole

Vitamin K antagonists
(inhibit II, VII, IX, X)

other: Tioclomarol

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	low-molecular-weight heparin (Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin) oligosaccharides (Fondaparinux Idraparinux) heparinoid (Danaparoid Sulodexide Dermatan sulfate)

Direct Xa inhibitors	xabans (Apixaban Betrixaban Edoxaban Otamixaban Rivaroxaban)

Direct thrombin (II) inhibitors

Other

Thrombolytic drugs/
fibrinolytics

plasminogen activators: r-tPA (Alteplase
Reteplase
Tenecteplase)
UPA (Urokinase
Saruplase)
Streptokinase^#
Anistreplase
Monteplase

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns

This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it.

Retrieved from "http://en.wikipedia.org/w/index.php?title=Antithrombotic&oldid=472046056"

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