Aortoiliac occlusive disease
|Aortoiliac occlusive disease|
|Classification and external resources|
Plate from Gray's Anatomy showing the abdominal aorta and the common iliac arteries.
In medicine, aortoiliac occlusive disease, also known as Leriche's syndrome and Leriche syndrome, is atherosclerotic occlusive disease involving the bifurcation of the abdominal aorta as it transitions into the common iliac arteries.
Classically, it is described in male patients as a triad of symptoms consisting of:
This combination is known as Leriche syndrome. However, any number of symptoms may present, depending on the distribution and severity of the disease, such as muscle atrophy and slow wound healing in the legs.
- Kissing balloon angioplasty +/- stent
- Aortoiliac bypass graft
- Axillofemoral and femoral-femoral bypass (sometimes abbreviated "ax-fem fem-fem")
The condition was first described by Robert Graham[disambiguation needed] in 1814, but the condition with its triad of symptoms was ascribed to René Leriche. Leriche, a French surgeon, linked the pathophysiology with the anatomy of the condition. John Hunter's dissections of atherosclerotic aortic bifurcations from the late 18th century are preserved at the Hunterian Museum, but Leriche was first to publish on the subject based on a patient he treated with the condition at the age of 30. Following treatment the 30 year old was able to walk without pain and maintain an erection.
- Lee BY, Guerra J (1994). "Axillofemoral bypass graft in a spinal cord injured patient with impending gangrene". The Journal of the American Paraplegia Society 17 (4): 171–6. PMID 7869060.
- McKinsey JF (1995). "Extra-anatomic reconstruction". Surg. Clin. North Am. 75 (4): 731–40. PMID 7638717.
- synd/2747 at Who Named It?
- Aortoiliac occlusive disease vascularweb.org
- Leriche's syndrome - whonamedit.com
- Coronal CT of Leriche' syndrome - learningradiology.com