Misra, Srivastava & Lata.
The genus Apophysomyces historically was monospecific, with the only species Apophysomyces elegans. However, recently were described three new species; Apophysomyces variabilis, Apophysomyces trapeziformis, and Apophysomyces ossiformis.
Among the other members of zygomycetes, Apophysomyces elegans mostly resembles those from genus Absidia. However, its bell-shaped (although not conical) apophyses (outgrowth), the existence of its foot-cell like hyphal segment, rhizoids produced opposite to the sporangiophores upon cultivation on plain agar, the darker and thicker subapical segment, and inability to sporulate on routine culture media help in distinguishing Apophysomyces elegans.
Apophysomyces elegans is a thermotolerant fungus: it has been found to grow favourably at temperatures of 26°C and 37°C, and it grows rapidly at 42°C. Its colonies are fluffy and cottony in appearance. The surface of the colony is white initially and turns to a brownish-grey or yellowish-cream as the culture ages, while the underside is white to pale yellow in colour.
Normally, no special precautions are needed with regard to this fungus.
Infection is usually acquired via traumatic implantations associated with soil or decaying vegetable matter (such as from accidental injuries or insect bites). Invasive soft tissue infections can develop on burns or wounds which are contaminated by soil. Unlike other zygomycosis, the affected host is usually otherwise immunocompetent. Apophysomyces elegans infections present most commonly as necrotizing fasciitis, osteomyelitis, and angioinvasion. Systemic and secondary renal and bladder infections have also been reported.
- Mucormycosis (specific term for infection caused by Mucoraceae family moulds)
- Zygomycosis (a more generic term for infection caused by Mucoraceae and various other mould varieties; the term Phycomycosis is also used).
- L. Collier, A. Balows, and M. Sussman, "Topley & Wilson's Microbiology and Microbial Infections", 9th ed. (1998), vol. 4. (London, Sydney, Auckland, New York). ISBN 0-340-80912-4 (ISBN is for 10th ed.)[page needed]
- Alvarez, Eduardo; Stchigel, Alberto M.; Cano, Josep; Sutton, Deanna A.; Fothergill, Annette W.; Chander, Jagdish; Salas, Valentina; Rinaldi, Michael G.; Guarro, Josep (2010). "Molecular phylogenetic diversity of the emerging mucoralean fungus Apophysomyces: Proposal of three new species". Revista Iberoamericana de Micología 27 (2): 80–9. doi:10.1016/j.riam.2010.01.006. PMID 20199897.
- Davise H. Larone, "Medically Important Fungi - A Guide to Identification", 3rd ed. (1995). (ASM Press, Washington, D.C.). ISBN 1-55581-172-8 (ISBN is for 4th ed.)[page needed]
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- Ribes, J. A.; Vanover-Sams, C. L.; Baker, D. J. (2000). "Zygomycetes in Human Disease". Clinical Microbiology Reviews 13 (2): 236–301. doi:10.1128/CMR.13.2.236-301.2000. PMC 100153. PMID 10756000.
- Cooter, RD; Lim, IS; Ellis, DH; Leitch, IO (1990). "Burn wound zygomycosis caused by Apophysomyces elegans". Journal of clinical microbiology 28 (9): 2151–3. PMC 268128. PMID 2229400.
- Lakshmi, V; Rani, TS; Sharma, S; Mohan, VS; Sundaram, C; Rao, RR; Satyanarayana, G (1993). "Zygomycotic necrotizing fasciitis caused by Apophysomyces elegans". Journal of clinical microbiology 31 (5): 1368–9. PMC 262941. PMID 8501244.
- Wieden, MA; Steinbronn, KK; Padhye, AA; Ajello, L; Chandler, FW (1985). "Zygomycosis caused by Apophysomyces elegans". Journal of clinical microbiology 22 (4): 522–6. PMC 268459. PMID 4077963.
- Lawrence, R.M.; Snodgrass, W.T.; Reichel, G.W.; Padhye, A.A.; Ajello, L.; Chandler, F.W. (1986). "Systemic zygomycosis caused byApophysomyces elegans". Medical Mycology 24 (1): 57–65. doi:10.1080/02681218680000071. PMID 3701543.
- Okhuysen, P. C.; Rex, J. H.; Kapusta, M.; Fife, C. (1994). "Successful Treatment of Extensive Posttraumatic Soft-Tissue and Renal Infections Due to Apophysomyces elegans". Clinical Infectious Diseases 19 (2): 329–31. doi:10.1093/clinids/19.2.329. PMID 7986910.