Arginine kinase

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arginine kinase
Identifiers
EC number 2.7.3.3
CAS number 9026-70-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an arginine kinase (EC 2.7.3.3) is an enzyme that catalyzes the chemical reaction

ATP + L-arginine \rightleftharpoons ADP + Nomega-phospho-L-arginine

Thus, the two substrates of this enzyme are ATP and L-arginine, whereas its two products are ADP and Nomega-phospho-L-arginine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:L-arginine Nomega-phosphotransferase. Other names in common use include arginine phosphokinase, adenosine 5'-triphosphate: L-arginine phosphotransferase, adenosine 5'-triphosphate-arginine phosphotransferase, ATP:L-arginine N-phosphotransferasel ATP:L-arginine, and omega-N-phosphotransferase. This enzyme participates in arginine and proline metabolism.

Structural studies[edit]

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1BG0, 1M15, 1M80, 1P50, 1P52, 1RL9, 1SD0, and 2J1Q.

References[edit]