Ariel Fernandez

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Ariel Fernandez
Fernandez copy2.tif
Born (1957-04-08)April 8, 1957
Bahía Blanca, Argentina
Residence Buenos Aires, Basel
Citizenship Argentina, USA
Fields Biophysics, statistical mechanics
Alma mater Yale University

Ariel Fernandez (born April 8, 1957) is an ArgentinianAmerican physical chemist.


He was born Ariel Fernandez Stigliano in Bahía Blanca, Argentina, and received a Licenciado degree in Mathematics in 1980 from the Universidad Nacional del Sur, Argentina. He then earned a Ph. D. in chemical physics from Yale University (New Haven, CT, USA) in 1984 and was a senior researcher in the division of Nobel laureate Manfred Eigen at the Max Planck Institute for Biophysical Chemistry in Goettingen, Germany. He held the Karl F. Hasselmann Chaired Professorship in Engineering at Rice University. He is a member of the National Scientific and Technical Research Council (CONICET) in Argentina.[1]


The research of Ariel Fernandez spans representation theory in algebra, applied mathematics, molecular biophysics, statistical mechanics and bioinformatics.,[2][3]

He developed the concept of the dehydron, a structural feature in a protein endowed with chemical functionality, consisting of an intramolecular hydrogen bond incompletely shielded from water attack, thereby endowed with a propensity to promote its own dehydration. Dehydrons cause epistructural tension in proteins and thus promote protein-protein interactions and protein-ligand associations.[4][5]


Camille and Henry Dreyfus Distinguished New Faculty, 1989; Camille and Henry Dreyfus Teacher-Scholar, 1991; Humboldt Award; John Simon Guggenheim Memorial Foundation Fellow, 1995;[6] Feinberg Fellow; State of Buenos Aires Medal; Eli Lilly Awardee; Honorary Member of Collegium Basilea (Switzerland); Elected Fellow, American Institute for Medical and Biological Engineering (2006).[7]


"Transformative Concepts for Drug Design: Target Wrapping", by Ariel Fernandez (ISBN 978-3642117916, Springer-Verlag, Berlin, Heidelberg, 2010).

Publications of Ariel Fernandez.[8]


  1. ^ Ariel Fernandez at CONICET (Argentine National Research Council)
  2. ^ CV for Ariel Fernandez
  3. ^ Ariel Fernandez Google Scholar Citations
  4. ^ Scientific American
  5. ^ Nature
  6. ^ "Ariel Fernández". Fellows. John Simon Guggenheim Memorial Foundation. Retrieved 27 September 2012. 
  7. ^ "College of Fellows". Members. American Institute for Medical and Biological Engineering. Retrieved 27 September 2012. 
  8. ^ "Ariel Fernandez Bibliography". Retrieved 25 February 2014.