Neutrophils typically have two or three lobes. In general, older neutrophils have more lobes than younger neutrophils. The Arneth count determines the percentage of neutrophils with one, two, three, four, and five or more lobes.
- Individuals who have a larger percentage of neutrophils with fewer lobes have a left shift which can be indicative of disease processes such as infection, malignant tumors, hemolytic crises, myocardial infarction, acidosis, etc.
- Individuals with a larger percentage of neutrophils with more lobes have a right shift and most commonly have diseases such as vitamin B12 or folate deficiency, chronic uremia, liver disease, etc.
The Arneth count is not commonly used in modern medicine, but is a frequent MCQ in PG entrance exams.