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Arse or ARSE may refer to:
- British English Anglo-Saxon word for the buttocks, usually replaced by the euphemistic "ass" in US/Canadian English.
- "arsehole", a similar British/Irish/Scottish/Australian term for the anus, equivalent to "asshole" in US/Canadian English.
- Arylsulfatase E, an arylsulfatase gene; deficiencies of it are associated with X-linked recessive chondrodysplasia punctata
- Animal Research - Scientific and Experimental, a fictional animal research centre in the book The Plague Dogs.
- Seigneurie d'Arse, a French wine from the Fitou region.
See also 
- Autonomous Rotorcraft Sniper System (ARSS), the U.S. army's experimental robotic weapons system
- The Army Rumour Service (ARRSE), an unofficial British Army website and forum
- Arses of Persia, king of Persia between 338 BC and 336 BC
- Arses, a genus of monarch flycatchers
- Ars, Latin for "art"
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