Arsenic acid, arsoric acid
|Molar mass||141.94 g/mol|
|Appearance||White translucent crystals,
|Melting point||35.5 °C (95.9 °F; 308.6 K)|
|Boiling point||120 °C (248 °F; 393 K) decomp|
|16.7 g/100 mL|
|Solubility||soluble in alcohol|
|Vapor pressure||55 hPa (50 °C)|
|Acidity (pKa)||2.19, 6.94, 11.5|
|EU classification||Toxic (T)
Dangerous for the environment (N)
|R-phrases||R23/25, R45, R50/53|
|S-phrases||S53, S45, S60, S61|
LD50 (Median lethal dose)
|48 mg/kg (rat, oral)|
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
|what is: / ?)(|
Arsenic acid is the chemical compound with the formula H3AsO4. More descriptively written as AsO(OH)3, this colorless acid is the arsenic analogue of phosphoric acid. Arsenate and phosphate salts behave very similarly. Arsenic acid as such has not been isolated, but only found in solution where it is largely ionized. Its hemihydrate form (H3AsO4·½H2O) does form stable crystals. Crystalline samples dehydrate with condensation at 100 °C.
Being a triprotic acid, its acidity is described by three equilibria:
- H3AsO4 + H2O H2AsO−
4 + H3O+ (K1 = 10−2.19)
4 + H2O HAsO2−
4 + H3O+ (K2 = 10−6.94)
4 + H2O AsO3−
4 + H3O+ (K3 = 10−11.5)
These Ka values are close to those for phosphoric acid. The highly basic arsenate ion (AsO3−
4) is the product of the third ionization. Unlike phosphoric acid, arsenic acid is an oxidizer, illustrated by its ability to convert iodide to iodine.
- As2O3 + 2 HNO3 + 2 H2O → 2 H3AsO4 + N2O3
Arsenic acid is slowly formed when arsenic pentoxide is dissolved in water, and when meta- or pyroarsenic acid is treated with cold water. Arsenic acid can also be prepared directly from elemental arsenic by moistening it and treating with ozone.
- 2 As + 3 H2O + 5 O3 → 2 H3AsO4 + 5 O2
Commercial applications of arsenic acid are limited by its toxicity. It has found occasional use as a wood preservative, broad-spectrum biocide, a finishing agent for glass and metal, and a reagent in the synthesis of some dyestuffs and organic arsenic compounds. The LD50 in rabbits is 6 mg/kg (0.006 g/kg).
- Holleman, A. F.; Wiberg, E. (2001). Inorganic Chemistry. San Diego: Academic Press. ISBN 0-12-352651-5.
- Lee, C.; Harrison, W. T. A. (2007). "Tetraethylammonium dihydrogenarsenate bis(arsenic acid) and 1,4-diazoniabicyclo[2.2.2]octane bis(dihydrogenarsenate) arsenic acid: hydrogen-bonded networks containing dihydrogenarsenate anions and neutral arsenic acid molecules". Acta Crystallographica C 63 (Pt 7): m308–m311. doi:10.1107/S0108270107023967. PMID 17609552.
- G. Brauer, ed. (1963). "Arsenic Acid". Handbook of Preparative Inorganic Chemistry 1 (2nd ed.). New York: Academic Press. p. 601.
- Joachimoglu, G. (1915). Biochemische Zeitschrift 70: 144. Missing or empty