Arteriosclerosis

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Arteriosclerosis
Classification and external resources
MeSH D001161

Arteriosclerosis refers to a stiffening of arteries.[1]

Arteriosclerosis is a general term describing any hardening (and loss of elasticity) of medium or large arteries (from the Greek arterio, meaning artery, and sclerosis, meaning hardening)

It should not be confused with "arteriolosclerosis" or "atherosclerosis".

Also known by the name "myoconditis" which is outdated and no longer in general use.

[edit] Types

  • Arteriosclerosis obliterans is typically seen in medium and large arteries of the lower extremity. Characterized by fibrosis of the intima and calcification of the media. The lumen of the vessel may be obliterated or markedly narrowed.
  • Medial calcific sclerosis (Monckeberg’s calcific sclerosis) is seen mostly in the elderly, commonly in arteries of the extremities. Characterized by calcification of the Tunica media but without thickening of the intima or narrowing of the vessel lumen. A similar form of an intramural calcification, presenting the picture of an early phase of arteriosclerosis, appears to be induced by a number of drugs that have an antiproliferative mechanism of action.[2][3]

[edit] References

  1. ^ "arteriosclerosis" at Dorland's Medical Dictionary
  2. ^ Arterial Vascular Effects of Non-steroidal Antiphlogistic Drugs - A Biochemical Model on an Intramural Induction of Arteriosclerosis, Rainer K Liedtke, MD
  3. ^ J. G. Mönckeberg: Über die reine Mediaverkalkung der Extremitätenarterien und ihr Verhalten zur Arteriosklerose. Virchows Archiv Jg. 1903, S. 141–167
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