These spores are asexual and are generally not as durable and environmentally persistent as, for instance, bacterial endospores or chlamydospores. Some medically significant pathogens, such as Coccidioides immitis, and Coccidioides posadasii, both causative agents of coccidioidomycosis (also known as San Joaquin Valley fever), are transmitted through airborne arthroconidia. The small size of the arthroconidia, 3 to 5 µm, allow them to lodge themselves into the terminal bronchioles of the lung. There, they develop into a thick-walled spherule filled with endospores that cause a pyogenic (pus-causing) inflammation.
- Sun SH, Sekhon SS, Huppert M. (1979). "Electron microscopic studies of saprobic and parasitic forms of Coccidioides immitis". Sabouraudia 17 (3): 265–73. PMID 531717.
- Neal JM, Rathmell JP. (2007). Complications in Regional Anesthesia and Pain Medicine. Elsevier Health Sciences. p. 76. ISBN 1-4160-2392-5.
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