Arthropods are covered with a tough or resistant exoskeleton, which may be mineralised or constructed of a tough polymer such as chitin, and is often biomineralized with materials such as calcium carbonate. This external skeleton is moulted as the organism grows.
Microscopic structure 
A typical arthropod exoskeleton is a multi-layered structure with four functional regions: epicuticle, procuticle, epidermis and basement membrane. Of these, the epicuticle is a multi-layered external barrier that, especially in terrestrial arthropods, acts as a barrier against desiccation. The strength of the exoskeleton is provided by the underlying procuticle, which is in turn secreted by the epidermis. Arthropod cuticle is a biological composite material, consisting of two main portions: fibrous chains of alpha-chitin within a matrix of silk-like and globular proteins, of which the most well-known is the rubbery protein called resilin. The relative abundance of these two main components varies from approximately 50/50 to 80/20 chitin protein, with softer parts of the exoskeleton having a higher proportion of chitin. Although the cuticle is relatively soft when first secreted, it soon hardens in a poorly-understood process that involves dehydration and/or tanning mediated by hydrophobic chemicals called phenolics. Different types of interaction between the proteins and chitin leads to varying mechanical properties of the exoskeleton.
In addition to the chitino-proteinaceous composite of the cuticle, many crustaceans, some myriapods and the extinct trilobites further impregnate the cuticle with mineral salts, above all calcium carbonate, which can make up up to 40% of the cuticle. This can lead to great mechanical strength.
Mechanical properties 
The two layers of the cuticle have different properties. The outer, sclerosed layer is very strong under compressive forces, but much weaker under tension. When it fails, it does so by cracking. The inner layer is not sclerosed, and is thus much softer; it is able to resist tensile forces but is liable to failure under compression.
This combination is especially effective in resisting predation, as predators tend to exert compression on the outer layer, and tension on the inner.
The degree of scleritisation affects how the cuticle responds to deformation. Below a certain point - and this point will be higher the more scleritised the cuticle is - deformation is elastic and the original shape is returned to after the stress is removed. Above this point, plastic (non-reversible) deformation occurs until finally the cuticle cracks.
The arthropod exoskeleton is typically divided into different functional units to allow flexibility in an often otherwise rigid structure. For example, the head is a fused capsule; and the trunk is often divided into a series of articulating sclerites called tergites. In addition, the characteristic limbs of arthropods need to be jointed. The internal surface of the exoskeleton is often elaborated into a set of specialised structures called apodemes that allow the attachment of muscles. Such endoskeletal components of the arthropod skeleton can be highly complex, as in crabs and lobsters.
- See also main article: Ecdysis
The relative rigidity of the exoskeleton means that continuous growth of arthropods is not possible. Therefore, growth is periodic and concentrated into a period of time when the exoskeleton is shed, called moulting or ecdysis, which is under the control of a hormone called ecdysone. Moulting is a complex process that is invariably dangerous for the arthropod involved. Before the old exoskeleton is shed, the cuticle separates from the epidermis through a process called apolysis. New cuticle is excreted by the underlying epidermis, and mineral salts are usually withdrawn from the old cuticle for re-use. After the old cuticle is shed, the arthropod typically pumps up its body (for example, by air or water intake) to allow the new cuticle to expand to a larger size: the process of hardening by dehydration of the cuticle then takes place. Newly molted arthropods typically appear pale or white, and darken as the cuticle hardens.