Arthur Harden

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Sir Arthur Harden
ArthurHarden.jpg
Born (1865-10-12)12 October 1865
Manchester, England
Died 17 June 1940(1940-06-17) (aged 74)
Bourne End, Buckinghamshire, England
Nationality United Kingdom
Fields Biochemistry
Institutions Lister Institute
Alma mater University of Manchester MSc,
University of Erlangen PhD
Doctoral advisor Otto Fischer
Known for the chemistry of the yeast cell
Notable awards Nobel Prize in Chemistry (1929)
Davy Medal (1935)

Sir Arthur Harden FRS[1] (12 October 1865 Manchester – 17 June 1940 Bourne End, Buckinghamshire) was an English biochemist. He shared the Nobel Prize in Chemistry in 1929 with Hans Karl August Simon von Euler-Chelpin for their investigations into the fermentation of sugar and fermentative enzymes.[2][3]

Biography[edit]

Early years[edit]

His parents were Albert Tyas Harden and Eliza Macalister. He was educated at a Tettenhall College, Staffordshire, and entered Owens College, now the University of Manchester, in 1882, graduating in 1885.

Research[edit]

In 1886 Harden was awarded the Dalton Scholarship in Chemistry and spent a year working with Otto Fischer at Erlangen. He returned to Manchester as lecturer and demonstrator, and remained there until 1897 when he was appointed chemist to the newly founded British Institute of Preventive Medicine, which later became the Lister Institute. In 1907 he was appointed Head of the Biochemical Department, a position which he held until his retirement in 1930 (though he continued his scientific work at the Institute after his retirement).

At Manchester, Harden had studied the action of light on mixtures of carbon dioxide and chlorine, and when he entered the Institute he applied his methods to the investigation of biological phenomena such as the chemical action of bacteria and alcoholic fermentation. He studied the breakdown products of glucose and the chemistry of the yeast cell, and produced a series of papers on the antiscorbutic and anti-neuritic vitamins.

Harden was knighted in 1926, and received several honorary doctorates. A Fellow of the Royal Society,[1] he received the Davy Medal in 1935.

Personal life[edit]

He was married with no children. His wife died in 1928.

See also[edit]

References[edit]

  1. ^ a b Hopkins, F. G.; Martin, C. J. (1942). "Arthur Harden. 1865-1940". Obituary Notices of Fellows of the Royal Society 4 (11): 2. doi:10.1098/rsbm.1942.0001.  edit
  2. ^ Manchester, K. (2000). "Arthur Harden: An unwitting pioneer of metabolic control analysis". Trends in Biochemical Sciences 25 (2): 89–92. doi:10.1016/S0968-0004(99)01528-5. PMID 10664590.  edit
  3. ^ Manchester, K. (2000). "Biochemistry comes of age: A century of endeavour". Endeavour 24 (1): 22–27. doi:10.1016/S0160-9327(99)01224-7. PMID 10824440.  edit