|Jmol-3D images||Image 1
|Molar mass||208.254 g mol−1|
|Appearance||colorless solid substance|
|Density||1.028 g/cm−3 |
|Melting point||62-63 °C |
|Boiling point||296 °C |
|Solubility in water||insoluble|
|Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)|
|(what is: / ?)|
Asarone, which includes alpha (trans) and beta (cis) types, is an ether found in certain plants such as acorus and asarum. As a volatile fragrance oil, it is used in killing plant fungal pests and bacteria. The toxicity and carcinogenicity of asarone means that it may be difficult to develop practical anthelmintics and insecticides based on it.
The main clinical symptom of asarone is prolonged vomiting that sometimes lasted more than 15 hours. Asarone is not metabolized to trimethoxyamphetamine as has been claimed by online vendors. Beta-asarone may be a potential candidate for development as a therapeutic agent to manage cognitive impairment associated with conditions such as Alzheimer's disease.
Notes and references
- Data for α-Asarone at ChemSpider
- "Asarone". The Merck Index. 14th edition. Merck Research Laboratories. 2006. p. 135. ISBN 978-0-911910-00-1.
- Beta asarone has CAS# 5273-86-9
- Suvarna Shenvi, Vinod, Rajendra Hegde, Anil Kush and G. Chandrasekara Reddy (2011). "A unique water soluble formulation of β-asarone from sweet flag (Acorus calamus L.) and its in vitro activity against some fungal plant pathogens". Journal of Medicinal Plants Research 5 (20): 5132–5137.
- Asha DS, Ganjewala D (2009). "Antimicrobial activity of Acorus calamus (L.) rhizome and leaf extract". Act. Biol. Szeg. 53 (1): 45–49.
- Perrett, Sheena; Whitfield, Philip J. (1995). "Anthelmintic and pesticidal activity ofAcorus gramineus (Araceae) is associated with phenylpropanoid asarones". Phytotherapy Research 9 (6): 405. doi:10.1002/ptr.2650090604.
- Björnstad K, Helander A, Hultén P, Beck O (2009). "Bioanalytical investigation of asarone in connection with Acorus calamus oil intoxications". J Anal Toxicol 33 (9): 604–9. doi:10.1093/jat/33.9.604. PMID 20040135.
- Geng Y. Li C. Liu J. Xing G. Zhou L. Dong M. Li X. Niu Y.Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats. Biological & Pharmaceutical Bulletin. 33(5):836-43, 2010.