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"Asp" is the modern Anglicisation of the word "aspis," which in antiquity referred to any one of several venomous snake species found in the Nile region. It is believed that the aspis referred to in Egyptian mythology is the modern Egyptian cobra.
Throughout dynastic and Roman Egypt, the asp was a symbol of royalty. Moreover, in both Egypt and Greece, its potent venom made it useful as a means of execution for criminals who were thought deserving of a more dignified death than that of typical executions. In some stories of Perseus, after killing Medusa, the hero used winged boots to transport her head to Mount Olympus. As he was flying over Egypt some of her blood fell to the ground, which transformed into asps.
According to Plutarch (quoted by Ussher), Cleopatra tested various deadly poisons on condemned persons and animals for daily entertainment and concluded that the bite of the asp (from aspis - Egyptian Cobra, not European Asp) was the least terrible way to die; the venom brought sleepiness and heaviness without spasms of pain. The asp is perhaps most famous for its alleged role in Cleopatra's suicide (some believe it to have been a horned viper), though in 2010, German historian Christoph Schaefer and toxicologist Dietrich Mebs, after extensive study into the event, came to the conclusion that rather than enticing a venomous animal to bite her, Cleopatra actually used a mixture of hemlock, wolfsbane and opium to end her life.
Nonetheless, the image of suicide-by-asp has become inexorably connected with Cleopatra, as immortalized by William Shakespeare:
With thy sharp teeth this knot intrinsicate
Of life at once untie: poor venomous fool
Be angry, and dispatch.
- —Cleopatra, Act V, scene II
- Antony and Cleopatra
Othello also famously compares his hatred for Desdemona as being full of "aspics' tongues" in Shakespeare's play Othello. (Act 3, scene iii)
See also 
- Schneemann, M.; R. Cathomas, S.T. Laidlaw, A.M. El Nahas, R.D.G. Theakston, and D.A. Warrell (August 2004). "Life-threatening envenoming by the Saharan horned viper (Cerastes cerastes) causing micro-angiopathic haemolysis, coagulopathy and acute renal failure: clinical cases and review". QJM: an International Journal of Medicine 97 (11): 717–27. doi:10.1093/qjmed/hch118. PMID 15496528. Retrieved 2009-09-04. "Whether Cleopatra used a snake as the instrument of her suicide has been long debated. Some favour the idea that she chose C. cerastes, but its venom is insufficiently potent, rapid and reliable. A more plausible candidate is the Egyptian cobra or 'asp' (Naja haje)"
- Lucan, Pharsalia, (c.61-65), trans. Robert Graves, book IX
- Crawford, Amy (April 1, 2007). "Who Was Cleopatra? Mythology, propaganda, Liz Taylor and the real Queen of the Nile". Smithsonian.com. Retrieved 4 September 2009.
- Kinghorn, A. M. (March 1994). "'All joy o' the worm' or, death by asp or asps unknown in act v of Antony and Cleopatra". English Studies 75 (2): 104–9. doi:10.1080/00138389408598902. Retrieved 2009-09-12. "The venomous reptile commonly known today as 'Cleopatra's asp' is a horned viper (Cerastes cornutus)"
- Melissa Gray (2010-06-30). "Poison, not snake, killed Cleopatra, scholar says - Cleopatra died a quiet and pain free death, historian alleges.". CNN. Retrieved 2012-04-13.