Astragalus propinquus

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Astragalus propinquus
Astragalus membranaceus.jpg
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Rosids
Order: Fabales
Family: Fabaceae
Genus: Astragalus
Species: A. propinquus
Binomial name
Astragalus propinquus
Schischkin[1]
Synonyms
  • "Astragalus membranaceus (Fisch.) Bunge
  • Astragalus membranaceus (Fisch.) Bunge var. mongholicus (Bunge)P.K.Hsiao
  • Astragalus propinquus Schischkin var. glabra Vydr.
  • Phaca membranacea Fisch."[1]

Astragalus propinquus (syn. Astragalus membranaceus[2] also known as huáng qí (Chinese: ), běi qí (Chinese: ) or huáng huā huáng qí (Chinese: 黄花黄耆),[3] is a flowering plant in the family Fabaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine.[4] It is a perennial plant and it is not listed as being threatened.[1]

Use[edit]

Herbalism[edit]

A. propinquus is used in traditional Chinese medicine for healing and for diabetes.[5] A. propinquus has been asserted to be a tonic that can improve the functioning of the lungs, adrenal glands and the gastrointestinal tract, increase metabolism and sweating, promote healing, and reduce fatigue.[6][medical citation needed]

Related species[edit]

The natural gum tragacanth, which is used in pharmaceuticals and textiles, is obtained from Astragalus tragacanthus.[7]

Medical[edit]

A. propinquus is an active component in Lectranal, a food supplement used in treatment of seasonal allergic rhinitis.[8]

Chemistry[edit]

An extract of A. propinquus called TA-65 can activate telomerase, extending the lengths of the shortest telomeres which protect the terminal DNA at the ends of all chromosomes.[9] It contains the saponin cycloastragenol. Constituents of the roots (Radix Astragali) include polysaccharides, triterpenoids (astragalosides)[10] as well as isoflavones (including kumatakenin, calycosin and formononetin) along with their glycosides and malonates.[11]

Toxicology[edit]

Other Astragalus spp. are known to cause severe poisonings in livestock due to indolizine alkaloids, aliphatic nitro compounds and accumulated selenium.[12] None of these constituents have been detected in the medicinal species Astragalus membranaceus used in dietary supplements and TCM preparations.[13][contradictory]

Compendial status[edit]

A. propinquus is listed in the following official Pharmacopeia:

  • Japanese Pharmacopoeia[14]

See also[edit]

Notes and references[edit]

  1. ^ a b c "Astragalus propinquus Schischkin". LegumeWeb. International Legume Database & Information Service. 2005-11-01. Retrieved 2012-02-27. 
  2. ^ http://www.ildis.org/LegumeWeb?version~10.01&LegumeWeb&tno~16104&genus~Astragalus&species~membranaceus
  3. ^ Joe Hing Kwok Chu. "Huang qi". Complementary and Alternative Healing University. Retrieved 2012-02-27. 
  4. ^ "Astragalus membranaceus - Moench.". Plants for a Future. 
  5. ^ "Astragalus". University of Maryland Medical Center (UMMC). 2007. Retrieved 2008-02-21. 
  6. ^ Balch, P. (2006). Prescription for Nutritional Healing (4th ed.). Avery Penguin Putnam. ISBN 978-1-58333-236-8. 
  7. ^ Gentry, H. S.; Mittleman, M.; McCrohan, P. R. (1990). "Introduction of Chia and Gum Tragacanth in the U.S.". Purdue University Crop Index. Purdue University. Retrieved 2012-02-26. 
  8. ^ Matkovic Z, Zivkovic V, Korica M, Plavec D, Pecanic S, Tudoric N. (2010). "Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis". 
  9. ^ Harley, C. B.; Liu, W.; Blasco, M.; Vera, E.; Andrews, W. H.; Briggs, L. A.; Raffaele, J. M. (2011). "A Natural Product Telomerase Activator As Part of a Health Maintenance Program". Rejuvenation Research 14 (1): 45–56. doi:10.1089/rej.2010.1085. PMC 3045570. PMID 20822369. 
  10. ^ Xu, Q.; Ma, X.; Liang, X. (2007). "Determination of Astragalosides in the Roots of Astragalus spp. Using Liquid Chromatography Tandem Atmospheric Pressure Chemical Ionization Mass Spectrometry". Phytochemical Analysis 18 (5): 419–427. doi:10.1002/pca.997. PMID 17624885. 
  11. ^ Lin, L. Z.; He, X. G.; Lindenmaier, M.; Nolan, G.; Yang, J.; Cleary, M.; Qiu, S. X.; Cordell, G. A. (2000). "Liquid Chromatography-Electrospray Ionization Mass Spectrometry Study of the Flavonoids of the Roots of Astragalus mongholicus and A. membranaceus". Journal of Chromatography A 876 (1–2): 87–95. doi:10.1016/S0021-9673(00)00149-7. PMID 10823504. 
  12. ^ Rios, J. L.; Waterman, P. G. (1997). "A Review of the Pharmacology and Toxicology of Astragalus". Phytotherapy Research 11 (6): 411–418. doi:10.1002/(SICI)1099-1573(199709)11:6<411::AID-PTR132>3.0.CO;2-6. 
  13. ^ "Astragalus". WebMD. 
  14. ^ Japanese Pharmacopoeia (15th ed.). 

External links[edit]