He was ordained in 1918 and was sent to Regina in 1922. He started an athletic club for boys and was appointed St. Augustine's parish in Wilcox, Saskatchewan in 1927.
Murray founded Notre Dame of the Prairies in 1927, and was the inspirational force behind the famous Notre Dame Hounds hockey team. Known as Père, he would never refuse a deserving student an education - even if that meant tuition was paid in potatoes and wheat rather than dollars and cents. Leading the college until his death, he influenced generations of Canadians and the development of Canadian hockey. Said Père Murray, "I love God, Canada and hockey -- not always in that order."
In 1968, he was made an Officer of the Order of Canada "for his contributions as President of the College of Notre Dame of Saskatchewan Inc. from which thousands of Canadian and foreign students from poorer families have graduated".